The Use of tDCS in the Orofacial Pain

Status Recruiting

Clinical Trial Summary

The trial´s main goal is to explore the use of transcranial direct current stimulation (tDCS) as a treatment option for persons suffering from orofacial pain. The aim of the trial is to further investigate the efficacy and longevity of tDCS in treating chronic pharmacoresistant orofacial pain. A prospective, randomized, double-blinded, two-arm, sham-controlled design will be utilized. Primarily, the analgesic effect's intensity and duration will be assessed. Secondarily, the associated reduction of symptoms of anxiety and depression will be investigated, as well as the impact on the general quality of life. Anodal stimulation (6 sessions in 2 weeks, 2mA, 20 min, cathode over the opposite Fp area) of M1 contralateral to the pain location will be employed. Washout periods of 48-72 hours will be kept between applications to improve neuroplasticity changes' induction, which is estimated to reflect in the effect retention. Eight major evaluation points will be employed in 26 weeks, and a daily numeric rating scale (NRS) self-assessment. The trial will potentially improve the quality of life, reduce the health burden caused by chronic orofacial pain, and provide further data on the use of tDCS in this setting, thus, enabling an additional route to manage the symptoms of pain in the future.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05584384
Study type	Interventional
Source	Charles University, Czech Republic
Contact	Jitka Fricova, M.D., Ph.D.
Phone	0042022496 6370
Email	jitka.fricova@vfn.cz
Status	Recruiting
Phase	N/A
Start date	October 3, 2022
Completion date	December 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04977349` - Manual Therapy Effectivity and Exercises in Musicians	N/A
Completed	`NCT00067366` - Brief Treatment for Temporomandibular Pain	N/A
Completed	`NCT06132594` - Computed Guided Prolotherapy Versus Conventional Prolotherapy	N/A
Not yet recruiting	`NCT03702101` - Detecting Auricular Points in OFP by a Novel APD ( APD-OFP)
Not yet recruiting	`NCT06065969` - Photobiomodulation Dosimetry s in Patients With Orofacial Pain	N/A
Completed	`NCT04352881` - Evaluation of Out of Hours Dental Emergency Treatments
Not yet recruiting	`NCT04765007` - Efficacy of Mindfulness Therapy in Orofacial Chronic Pain	N/A
Terminated	`NCT01883245` - Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Chronic Orofacial Pain	Phase 2
Completed	`NCT00899717` - Occlusal Adjustment as Treatment for Chronic Orofacial Pain	Phase 1/Phase 2
Recruiting	`NCT05430776` - Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients	N/A
Active, not recruiting	`NCT03710967` - Bilateral TMS vs. Unilateral TMS	N/A
Recruiting	`NCT04694274` - Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Completed	`NCT01327157` - Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis	N/A
Enrolling by invitation	`NCT06405646` - Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
Not yet recruiting	`NCT05961501` - The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin	Phase 2/Phase 3
Completed	`NCT01949064` - Use of Electromyography With Bio-Feedback for the Treatment of Craniomandibular Disorders	Phase 2
Recruiting	`NCT05562635` - CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)	Phase 2/Phase 3
Completed	`NCT04524806` - Influence of Stabilization Splint Thickness on The Temporomandibular Disorders	N/A
Completed	`NCT03221946` - A Comparative Evaluation of Diclofenac Sodium Transdermal Patch, Oral Diclofenac Sodium With Intramuscular Injections of Diclofenac Sodium in Patients Suffering From Oral Pain	Phase 4
Completed	`NCT04612855` - Post-traumatic Neuropathy of the Trigeminal Nerve