Organ Donation Clinical Trial
Official title:
Understanding Decision Making in the Intensive Care Unit: a National Study
Given how central Substitute Decision Makers (SDMs) are to the process leading to end of life decisions and sometimes, organ donation, it is striking how poorly understood this decision-making process is. A 2017 scoping review on the topic of soliciting SDM consent to organ donation reported on more than 168 studies covering a broad range of topics, including: SDM characteristics and predictors of consent; the process of soliciting consent; and the effect of the decision on subsequent process of care and on family well-being. An unexplored area, however, is factors - including modifiable factors - that influence SDM decision making at the end of life, which organ donation is part of, such as: responses to stress, support from extended families and friends, and personal beliefs about the ongoing medical conditions. This project seeks to fill this clear and important gap. In the ICU, at the end of life, SDMs are under incredible emotional distress, have often not eaten or slept properly for days preceding discussions about end of life and organ donation, and are also in the midst of grieving for their loved one. The time pressure poses challenges for SDMs' decision making. Thus, this study will investigate novel, potentially modifiable reasons for end of life decision so that we may better support this personally challenging and important decision, especially if organ donation decision interferes with the decision process. Primary objective: To investigate beliefs and experiences of SDMs involved in the decision-making process around withdrawal of life sustaining therapies . Secondary objective: To inform efforts to improve support for SDMs with the aim of improving the decision-making process end-of-life decisions, including when organ donation is involved.
A national multicenter multi-methods study with SDMs will be conducted in two steps. In Step 1, a semi-structured interviews with SDMs will be conducted. The sampling frame will balance interviews with those that were approached or not for organ donation, and consented or not to organ donation. Interviews will be informed by two complementary theoretical frameworks. Building on Step 1 results, in Step 2 a national telephone survey of SDMs will be conducted to test which factors are associated with end-of-life decisions. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03213171 -
Promoting Organ Donor Registration in Family Physician Offices
|
N/A | |
Completed |
NCT03816241 -
Mechanisms of Nudges on Families' Decision-Making Process
|
N/A | |
Completed |
NCT04007419 -
Health Promoters and Organ Donation
|
N/A | |
Completed |
NCT01969864 -
University Student Intervention to Increase Organ Donation
|
N/A | |
Completed |
NCT02836301 -
RCT- Comparing Testimonial Versus Documentary Organ Donation Video Education
|
N/A | |
Completed |
NCT03612024 -
Bernese Next of Kin Survey Following Organ Donation Request
|
||
Completed |
NCT03179020 -
Donation Network to Optimize Organ Recovery Study
|
N/A | |
Recruiting |
NCT05660252 -
Effect of Collaborative Requesting on DCD Refusal Rates: Randomized Controlled Trial
|
N/A | |
Terminated |
NCT03439995 -
Goal of Open Lung Ventilation in Donors
|
N/A | |
Completed |
NCT02525510 -
Deceased Organ Donor Interventions to Protect Kidney Graft Function
|
N/A | |
Completed |
NCT02854267 -
Organ Procurement : Usefulness of a Guide for Meeting With the Next of Kin
|
||
Completed |
NCT02138227 -
A Randomized Trial of the Early Referral and Request Approach (ERRA) Intervention to Increase Consent to Organ Donation
|
N/A | |
Recruiting |
NCT04661787 -
Donation Advisor Clinical Decision Support Tool Study
|
||
Completed |
NCT02825862 -
Investigating Affective Attitude Question-behaviour Effects on Intention to Become an Organ Donor
|
N/A | |
Recruiting |
NCT03786991 -
EPI-STORM: Cytokine Storm in Organ Donors
|
||
Recruiting |
NCT04734574 -
Methods of Confirmation of Brain Death
|