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Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

Oral Lichen Planus Clinical Trial

Official title:
Efficacy and Safety of Baricitinib for the Treatment of Oral Lichen Planus: A Proof-of-Concept Study

Clinical Trial Summary

The goal of this clinical trial is to learn the effects of baricitinib (the study drug) in patients with Oral Lichen Planus. The main questions it aims to answer are: - What is the efficacy of baricitinib in treating moderate to severe Oral Lichen Planus? - Can baricitinib treatment in Oral Lichen Planus change quality of life? - What side effects do patients with Oral Lichen Planus experience when treated with baricitinib? Participants will be required to come in to monthly visits for up to eight months. During visits, participants will be: - Evaluated for the extent of their disease - Asked to fill out a questionnaire about their quality of life - Given baricitinib for them to take at home for six months - Evaluated for any potential side experienced while on treatment - Asked to return 1 month after completing treatment

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06158113
Study type Interventional
Source University of North Carolina, Chapel Hill
Contact Erika Hanami
Phone 984-974-3682
Email erika_hanami@med.unc.edu
Status Recruiting
Phase Phase 2
Start date March 13, 2024
Completion date March 2025
View Details
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