Oral Health Clinical Trial
Official title:
To Exam the Efficacy of Oral Health and Mediterranean Diet Interventions in Preventing Cognitive Decline Among Older Adults With Mild Cognitive Impairment
Verified date | May 2023 |
Source | Taipei Veterans General Hospital, Taiwan |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
At present, many literatures have confirmed that the Mediterranean diet has the effect of delaying cognitive degeneration in patients with mild cognitive impairment, and can also slow down the speed of brain atrophy. In addition to the highly respected Mediterranean diet every year, several years of foreign research have found The maintenance of oral hygiene also has a significant relationship with the decline of cognitive function. The intervention of "oral hygiene" is a new intervention method that has started in recent years. Oral health will affect the overall health status, physical function, diet and nutritional status of the elderly. In particular, older adults with poor oral health are more likely to suffer from mild cognitive impairment. The relationship between oral health and nutrition and overall health is inseparable. If the concept of healthy eating (Mediterranean diet) recognized by the public is used and oral health education is involved at the same time. To allow patients with mild cognitive impairment to maintain oral health care in daily life, and to increase the knowledge of the Mediterranean diet and try to follow the rules of the Mediterranean diet, whether there is a more significant impact on these patients.
Status | Recruiting |
Enrollment | 120 |
Est. completion date | December 31, 2023 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 50 Years and older |
Eligibility | Inclusion Criteria: 1. Over or equal to 50 years old 2. CDR score is less than or equal to 0.5 or MMSE score is 24-30 (including 24 and 30) 3. Conscious/complaint of cognitive decline Exclusion Criteria: 1. Dementia 2. Acute and significant mental illness in the past three months 3. Acute serious medical and surgical diseases in the past three months 4. Symptoms of delusions, hallucinations or delirium in the past three months 5. Severe visual and hearing impairment in the past three months 6. Other conditions that make the patient unable to cooperate: such as not being suitable after screening, not signing the subject's consent form. |
Country | Name | City | State |
---|---|---|---|
Taiwan | Taipei Veterans General Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
Taipei Veterans General Hospital, Taiwan | National Yang Ming Chiao Tung University |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | cognitive | MoCA&MMSE | 6 months | |
Primary | diet | MEDAS-14 item | 6 months | |
Primary | oral health | OHAT | 6 months | |
Primary | frailty | Frailty Criteria | 6 months |
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