Clinical Trials Logo
  1. Home
  2. Optic Nerve Diseases
  3. NCT01270126

Trial of Alternating Current Stimulation in Optic Neuropathy — SCT_optnerve  

Optic Nerve Diseases Clinical Trial

Official title:
Treatment of Patients With Optic Neuropathy Using Transorbital Alternating Current Stimulation - a Randomized Trial

Clinical Trial Summary

Non-invasive brain stimulation can increase cortical excitability in the visual system, but it is not known if this is of clinical value. The investigators now assessed if repetitive, transcranial alternating current stimulation (rtACS) can improve visual field size in patients with optic nerve damage. The investigators hypothesized that rtACS would improve visual functions within the defective visual field sectors of the visual field (primary outcome measure).

Clinical Trial Description

In a prospective, double-blind, randomized, placebo-controlled clinical trial 22 patients with optic nerve damage were randomly assigned to a rtACS- (n=12) or placebo-group (n=10). Visual field measures, visual acuity and EEG-recordings were collected before and after a daily 20-40min treatment for 10-days and at a 2-months-follow-up. Primary outcome measure was detection accuracy (DA) in defective visual field sectors of computer-based high resolution perimetry (HRP). Secondary outcome parameters included DA in static and kinetic perimetry, reaction time (RT) in HRP, visual acuity (VA), contrast vision, and EEG power spectra. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01270126
Study type Interventional
Source University of Magdeburg
Contact
Status Completed
Phase N/A
Start date November 2006
Completion date December 2010
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05130385 - High Resolution Optical Coherence Tomography
Terminated NCT01422525 - Changes of the Peripapillary Retinal Nerve Fiber Layer After Filtration Surgery in Glaucoma Patients N/A
Terminated NCT00359632 - Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater Phase 3
Not yet recruiting NCT04289909 - Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS) N/A
Active, not recruiting NCT02376881 - Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study) Phase 3
Completed NCT04125043 - Accuracy of the Red Reflex Test in the Pediatric Population
Completed NCT02582164 - Long-Working Distance OCT for Children N/A
Recruiting NCT06139523 - Optimize Pediatric OCT Imaging
Completed NCT01404247 - Spectral Domain Optical Coherence Tomography Imaging of the Eyes of Neonates Phase 1
Recruiting NCT05626426 - Electrical Stimulation for the Treatment of Optic Neuropathies N/A
Completed NCT04891211 - Retinal Changes in Vitamin D Deficiency N/A
Completed NCT01280877 - Paraorbital-Occipital Alternating Current Stimulation Therapy for Optic Neuropathy (MCT_optnerve) N/A
Recruiting NCT04634383 - A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness N/A