Opioid Withdrawal Clinical Trial
Official title:
Lofexidine for Rapid Pre-Operative Opioid Tapering in Adults Undergoing Lumbar Spine Surgery
The primary objective is to investigate the effects of lofexidine in adults undergoing opioid tapering prior to elective lumbar spine surgery.
In this clinical trial, an open label design will be used to facilitate opioid tapering during a 12-day period prior to elective spine surgery. The primary outcome measure of this study is the number of patients who achieve a 50% reduction in daily opioid dose at day 12. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04080037 -
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
|
N/A | |
Completed |
NCT04140955 -
Opioid Tapering After Spine Surgery
|
N/A | |
Not yet recruiting |
NCT03813095 -
Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
|
Phase 2 | |
Completed |
NCT01262092 -
Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals
|
Phase 2 | |
Completed |
NCT04075214 -
Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal
|
N/A | |
Recruiting |
NCT04325659 -
An Innovative Intervention for OUD Treatment
|
Phase 2/Phase 3 | |
Withdrawn |
NCT03678792 -
Comparison of Three Opioid Detoxification Treatment Regimens
|
Phase 3 | |
Terminated |
NCT04162145 -
BRIDGE Device for Treatment of Opioid Withdrawal
|
N/A | |
Completed |
NCT04238754 -
Oral Cannabidiol for Opioid Withdrawal
|
Phase 1/Phase 2 | |
Recruiting |
NCT05053503 -
Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder
|
N/A | |
Recruiting |
NCT05555485 -
Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain
|
N/A | |
Active, not recruiting |
NCT03485430 -
Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months Follow up
|
N/A | |
Recruiting |
NCT05790551 -
Suboxone Dispenser for OUD
|
N/A | |
Completed |
NCT03174067 -
Buprenorphine in the Emergency Department
|
Phase 4 | |
Completed |
NCT04731935 -
Novel Earpiece for Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal
|
N/A | |
Completed |
NCT04470050 -
Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT06442566 -
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
|
Phase 1/Phase 2 | |
Recruiting |
NCT05307458 -
Evaluating the Pharmacokinetics and Patient Outcomes of Buprenorphine Microdosing
|
||
Completed |
NCT03789214 -
Medical Management of Sleep Disturbance During Opioid Tapering
|
Phase 2 | |
Recruiting |
NCT04759703 -
Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
|
Phase 2/Phase 3 |