Opioid-use Disorder Clinical Trial
— BEDOfficial title:
Buprenorphine in the Emergency Department: Buprenorphine Versus Clonidine for Opioid Withdrawal
Verified date | May 2017 |
Source | St. Joseph's Health Centre Toronto |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This is a pilot randomized control trial randomizing patients presenting in opioid withdrawal to the emergency department to receive either one of clonidine (usual standard of care) or buprenorphine for their opioid withdrawal. Primary treatment outcome is attendance at a rapid access addiction medicine clinic within a few days of emergency room presentation. Secondary treatment outcome is treatment status with respect to opioid agonist treatment at one month post emergency room visit.
Status | Completed |
Enrollment | 26 |
Est. completion date | November 2016 |
Est. primary completion date | April 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years and older |
Eligibility |
Inclusion Criteria: 1. Presenting to the ED in opioid withdrawal or soon to be in withdrawal 2. Minimum age 16 3. English speaking 4. Active phone number 5. Ontario Health Insurance Program card Exclusion Criteria: 1. Pregnant 2. Currently enrolled in a methadone or buprenorphine maintenance 3. Benzodiazepine addiction (or taking >50mg of valium equivalent/day) 4. Acute hepatitis or liver failure |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
St. Joseph's Health Centre Toronto |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of participants attending the rapid access clinic | The number of participants who attend a rapid access clinic assessment after initial enrollment | 2-5 days | |
Secondary | Number of participants who are on opioid agonist treatment | The number of participants who are maintained on some form of opioid agonist treatment at the one-month mark | 30 days |
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