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Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain

Opioid-induced Constipation Clinical Trial

Official title:
Risk of Major Adverse Cardiovascular Events Among Users of Naldemedine Compared With Other Medications Used for Opioid Induced Constipation in Adult Patients With Chronic Non-Cancer Pain in a Healthcare Claims Database

Clinical Trial Summary

The research objective is to characterize the risk of a major adverse cardiovascular event (MACE) among new users of naldemedine versus new users of lubiprostone and new users of naloxegol as comparator opioid induced constipation (OIC) medications.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03720613
Study type Observational
Source BioDelivery Sciences International
Contact Todd Kunkel
Phone 913-940-1789
Email tkunkel@bdsi.com
Status Recruiting
Phase
Start date January 4, 2019
Completion date November 1, 2030
View Details
See also
  Status Clinical Trial Phase
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Completed NCT04173858 - Evaluation of the Quality of Life of Patients With Opioid-induced Constipation Under Treatment With Naloxegol
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Completed NCT02270983 - Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain Phase 2
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