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A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus

Onychomycosis Clinical Trial

Official title:
A Randomized, Double-Blind, Multiple-Dose, Placebo-Controlled Tolerability And Pharmacokinetic Study Of Escalating Doses Of Albaconazole In Healthy Subjects

Clinical Trial Summary

The purpose of this study is to determine an upper dose of albaconzole to be administered in a Thorough QTc study.

Clinical Trial Description

This study aims to evaluate the safety and tolerability of 5 days of albaconazole dosing at levels that exceed both the projected therapeutic dose and the projected therapeutic frequency, in order to identify an upper dose for administration in a TQTc study. It also aims to assess the pharmacokinetics of multiple escalating doses of albaconazole, and to assess the effects of multiple and sustained dosing of high doses of albaconazole on ECG parameters. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01014962
Study type Interventional
Source GlaxoSmithKline
Contact
Status Completed
Phase Phase 1
Start date August 24, 2009
Completion date December 4, 2009
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