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Onychomycosis clinical trials

View clinical trials related to Onychomycosis.

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NCT ID: NCT04188574 Completed - Fungal Infection Clinical Trials

A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail

Start date: March 22, 2021
Phase: Phase 2
Study type: Interventional

This study will be a multicenter, international, randomized, vehicle-controlled, parallel-group, double-blinded study. Subjects who are eligible to participate with a confirmed diagnosis of Distal Subungual onychomycosis (DSO) of the toenail will be randomized and participate in one of the following treatment groups: BB2603-1: 0.01% terbinafine/0.03% polyhexanide formulation, or BB2603-3: 0.03% terbinafine/0.09% polyhexanide formulation, or BB2603-10: 0.1% terbinafine/0.3% polyhexanide formulation, or Vehicle: 0.3% polyhexanide/20% ethanol/water formulation. The subject in each treatment group will be treated twice daily (BID) for 12 weeks and then complete a 28-day post-treatment visit.

NCT ID: NCT04084782 Recruiting - Clinical trials for Onychomycosis of Toenail

An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.

Start date: August 13, 2019
Phase:
Study type: Observational

To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.

NCT ID: NCT04042857 Recruiting - Clinical trials for Onychomycosis of Toenail

Safety and Efficacy of Next Science Gel on Toenail Fungus

Start date: July 26, 2019
Phase: N/A
Study type: Interventional

This is a 52 week, 20-patient open-label pilot study on the safety and efficacy of Next Science Wound gel in the treatment of mild to moderate Distal Subungual Onychomycosis.

NCT ID: NCT03814343 Completed - Onychomycosis Clinical Trials

Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis

amphotericin
Start date: January 15, 2019
Phase: Phase 4
Study type: Interventional

The randomized control trial study aimed to evaluate effectiveness and safety of amphotericin B in 30% DMSO solution comparing with 30% DMSO solution in NDMs onychomycosis treatment.

NCT ID: NCT03405818 Completed - Onychomycosis Clinical Trials

An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents

Start date: October 22, 2015
Phase: Phase 4
Study type: Interventional

This was an open-label study to evaluate the safety and pharmacokinetics of tavaborole 5% topical solution in treating distal subungual onychomycosis (a fungal infection) of the toenail in children and adolescents (ages 6 to 16 years). Following confirmation of eligibility, including laboratory evidence of a fungal organism in the toenail, tavaborole topical solution was applied once daily to all affected toenails for a 48-week treatment period. Clinical assessment of the extent of infection and safety assessments were performed periodically throughout the 48-week treatment period, and again at 52 weeks (4 weeks after stopping the treatment). A subgroup of enrolled subjects applied the topical solution to all 10 toenails and a small area of surrounding skin during the first 28 days. These subjects had blood samples analyzed to evaluate the pharmacokinetics (how the drug moves in the body) of tavaborole topical solution in children and adolescents.

NCT ID: NCT03382717 Completed - Clinical trials for Onychomycosis of Toenail

Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis

Start date: October 26, 2016
Phase: N/A
Study type: Interventional

This study evaluates the effect of the medical device "Excilor® Forte" in the treatment of toenail onychomycosis. Half of the participants will receive the tested product and the other half will receive a comparator (Amorolfin 5%). Patients will be followed during 6 months.

NCT ID: NCT03289871 Completed - Onychomycosis Clinical Trials

Clinical Evaluation of the Efficacy of a Medical Device in Treatment of Toenail Onychomycosis

Start date: January 2015
Phase: N/A
Study type: Interventional

This study evaluates the effect of the medical device "Excilor® Fungal Nail Infection" in the treatment of toenail onychomycosis. Half of the participants will receive the tested product and the other half will receive a comparator (Amorolfin 5%). Patients will be followed during 6 months.

NCT ID: NCT03280927 Completed - Clinical trials for Mild to Moderate Onychomycosis Due to Dermatophyte

Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Jublia® in Mild to Moderate Toenail Onychomycosis

Start date: November 10, 2017
Phase: Phase 4
Study type: Interventional

The antifungal efficacy and safety of Jublia® topical solution will be assessed through an administration for 48 weeks to patients diagnosed with a mild or moderate onychomycosis due to dermatophyte.

NCT ID: NCT03244280 Completed - Onychomycosis Clinical Trials

A Study of the Systemic Absorption of MOB015B

Start date: December 16, 2017
Phase: Phase 1
Study type: Interventional

A Study of the Systemic Absorption of Once Daily MOB015B when Applied for 28 Days in Subjects with Moderate to Severe Onychomycosis of the Toenails.

NCT ID: NCT03216200 Completed - Onychomycosis Clinical Trials

Early Feasibility Study to Evaluate the Efficacy of the RenewalNailâ„¢ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)

Start date: July 7, 2017
Phase: N/A
Study type: Interventional

A study to determine if a three-treatment protocol with the RenewalNailâ„¢ plasma treatment system over a week will result in mycological cure and/or clear nail growth on the treated hallux toe.