Clinical Trials Logo

Clinical Trial Summary

This study aims to assess if laser treatment can cure fungal infection in toenails. Nail clippings from eligible subjects were obtained and randomised into two groups. All nail clippings were treated once with a 1064 nm Nd:YAG-laser. Before and after treatment, nail clippings were tested for fungal infection by microscopy and by culture.


Clinical Trial Description

This study was carried out as a randomised controlled trial (RCT) including two treatment groups subjected to two different laser treatments. A 1064 nm Nd:YAG-laser (Candela Medical, Ellipse Nordlys (Nd:YAG 1064), USA) was used for all treatments. Potential subjects were recruited from general practitioners and skin clinics in North Jutland from August 24th, 2021, through December 2021. All interventions and mycological tests for each subject were performed over the course of one day. After subjects were included, toenails with a clinical suspicion of onychomycosis (OM) were tested for fungal infection by culture and microscopy. At the same time, nail clippings from said toenails were obtained and randomised into one of two treatment groups, i.e., group A and group B. The nail clippings were then treated with a 1064 nm Nd:YAG-laser with laser settings as specified by the treatment groups. All nail clippings were treated only once. Immediately after treatment, nail clippings were again tested for fungal infection by culture and microscopy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05260450
Study type Interventional
Source Aalborg University Hospital
Contact
Status Completed
Phase N/A
Start date October 4, 2021
Completion date December 6, 2021

See also
  Status Clinical Trial Phase
Completed NCT03110029 - Evaluating the Efficacy and Compatibility of Efinaconazole 10% Solution (Jublia) for the Treatment of Toenail Onychomycosis in Patients Wearing Toenail Polish Compared to Those Without Polish Phase 4
Active, not recruiting NCT05110638 - Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis Phase 1
Completed NCT03382717 - Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis N/A
Not yet recruiting NCT06417983 - Topical Application of Essential Oils to Treat Onchomycosis
Withdrawn NCT03094468 - Study to Evaluate the Efficacy and Safety of P-3058 Nail Solution in the Treatment of Onychomycosis Phase 3
Recruiting NCT05674747 - Pilot Study of Swift Microwave Device for Onychomycosis Phase 1/Phase 2
Recruiting NCT06006455 - Effect of the Erchonia® LunulaLaserâ„¢ for the Treatment of Toenail Onychomycosis N/A
Not yet recruiting NCT03098342 - Comparison of Efficacy and Safety Between Methylene Blue-mediated Photodynamic Therapy and 5% Amorolfine Nail Lacquer for Toenail Onychomycosis Treatment N/A
Completed NCT03216200 - Early Feasibility Study to Evaluate the Efficacy of the RenewalNailâ„¢ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail) N/A
Recruiting NCT04042857 - Safety and Efficacy of Next Science Gel on Toenail Fungus N/A
Active, not recruiting NCT05135910 - To Evaluate Hallux Terbinafine Subungual Gel (HSG) in the Treatment of Onychomycosis Phase 2
Active, not recruiting NCT05139888 - Light Therapy for Onychomycosis Study N/A
Completed NCT04961684 - Clinical Evaluation of Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis N/A
Completed NCT03141840 - Clinical Trial of Topical ABL01 Treatment of Onychomycosis N/A
Recruiting NCT04084782 - An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
Withdrawn NCT03066336 - A Study to See if Low Level Laser Light Can Help to Treat Toenail Fungus N/A