The Effect of Exercise on Cognitive Status in Older Adults

Older People Clinical Trial

Official title:

Is Aerobic and Dual-task Training Combination the Most Effective Exercise Combination to Improve the Cognitive Status and Physical Function in Older Adults With Mild Cognitive Decline

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05532371
• Other study ID #: Gazi University
• Status: Completed
• Phase: N/A
• Start date: January 30, 2019
• Est. completion date: February 1, 2020

Study information

• Verified date: September 2022
• Source: Mugla Sitki Koçman University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to demonstrate the effectiveness of the different combinations of exercises on the cognitive status of older adults with cognitive decline.

Description:

This study is planned to examine the effects of combined exercise on cognitive status, lower extremity muscle strength, mobility, physical performance, mood and quality of life in older adults with Mild Cognitive Impairment. Aerobic exercise training and lower limb (extremity) strengthening exercises were applied to the first group, dual-task training and lower limb strengthening exercises were applied to the second group, and aerobic exercise training, dual-task training and lower limb strengthening exercises were applied to the third group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: February 1, 2020
• Est. primary completion date: December 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Not had a fall in the last six months.

• Older adults with an mini mental state examination score between18-23.

• Age = 65years.

Exclusion Criteria:

• having central nervous system pathology that will affect balance

• diagnosed with vestibular pathology,

• having deformities in the waist, hip, and knee joints,

• having lower extremity amputation,

• with lower extremity operation history,

• malignancy affecting the lower extremity,

• having moderate and severe congenital heart disease, coronary heart disease and cerebrovascular disease,

• participants who cannot cooperate,

• participants who use an assistive walking device,

• participants having vision problems.

Related Conditions & MeSH terms

• Older People

Intervention

Other:
• Aerobic exercise training combined with lower limb strengthening
The participants performed aerobic exercise training and lower limb strengthening during this intervention.
• Dual-task training combined with lower limb strengthening group (DG)
The participants performed dual-task training combined with lower limb strengthening during this intervention.
• Aerobic exercise training combined with dual-task training and lower limb strengthening
The participants performed aerobic exercise training combined with dual-task training and lower limb strengthening during this intervention.
• Only lower limb strengthening group (CG)
The participants performed only lower limb strengthening group during this intervention.

Locations

Country	Name	City	State
Turkey	Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Mugla Sitki Koçman University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mini-Mental State Examination	Cognitive status examination is applied with a simple test called "Mini-Mental State Examination".	12 weeks
Primary	Commander Power Track 2 Manual Tester	Muscle strength strength is carried out with "Commander Power Track 2 Manual Tester".	12 weeks
Primary	Timed Up and Go Test	Functional mobility is evaluated by Timed Up and Go Test.	12 weeks
Primary	Single Leg Stance Test	Static balance is evaluated by Single Leg Stance Test	12 weeks
Primary	Activities-specific Balance Confidence Scale	Balance Confidence is evaluated by Activities-specific Balance Confidence Scale.	12 weeks
Primary	Six-Minute Walk Test	Exercise capacity is evaluated by Six-Minute Walk Test.	12 weeks
Primary	Short Physical Performance Battery	Physical performance is evaluated by Short Physical Performance Battery.	12 weeks
Primary	Hamilton Depression Rating Scale	Emotional status is evaluated by Hamilton Depression Rating Scale	12 weeks
Primary	World Health Organization Quality of Life-Old module	Quality of life is evaluated by World Health Organization Quality of Life-Old module	12 weeks