The Esbjerg Cohort - A Cross-sectional Study About Work Ability and Musculoskeletal Pain in 55 to 70 Years Old Workers

Occupational Exposure Clinical Trial

Official title:

Ergonomic Exposure in Relation to Physical Capacity and Its Effect on Work Ability and Musculoskeletal Pain in the Oldest Group of Workers - The Esbjerg Cohort

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05811767
• Other study ID #: esbjerg_cohort
• Status: Completed
• Start date: November 14, 2022
• Est. completion date: April 15, 2024

Study information

• Verified date: April 2024
• Source: Hospital of South West Jutland
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The overall aim of this study is to investigate how work with physical demands affects the physical capacity, work ability, labor market affiliation, pain and self-reported health in the oldest group of workers.

Following research questions are to be answered:

1. How high physical work demands affects muscle strength in 55-70-year-old workers and how obesity in combination with high physical work exposure influences muscle strength, work ability, cardiac function, and self-reported health?

2. Which parameters are important for work ability and how does the exposure of high physical workload affect the work ability over time in 55-70-year-old workers?

3. By exploring the underlying mechanism of pain among 55+ year old workers, how is pain associated with work ability, BMI and physical capacity?

Description:

This study is a population-based cross-sectional study conducted in the municipality Esbjerg, Denmark. This study wants to investigate how ergonomic exposure in relation to physical capacity has an effect on work ability and musculoskeletal pain in workers between 55 and 70 years old. This Ph.D. is a clinical study including physical tests, questionnaires, and long-term evaluation of work ability. The study population consists of 336 citizens divided into 12 groups stratified for gender, age (< 60 years, 60-64 years and above 64 years) and occupational group (white-collar or blue-collar worker).

The study population will be recruited to uncover the physical workload among citizens 55+ years and compare the physical work demands to their health status, pain and physical capacity. The intention is to provide knowledge of the consequences of high physical workload on the musculoskeletal system in the oldest group of workers. This knowledge is necessary for better treatment and counseling to the oldest group of workers and for improved guidelines on how to optimize the balance between the physical work demands and the capacity of the workers.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 331
• Est. completion date: April 15, 2024
• Est. primary completion date: April 15, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 55 Years to 70 Years

Eligibility

Inclusion Criteria:

• Men and women born between 1952 and 1966

• Living in the Esbjerg municipality

• Able to write, read and understand Danish

Exclusion Criteria:

• Injuries to arms or legs (e.g arm in plaster, acute trauma on ACL)

• Just had a surgery (e.g an operation in the abdominal region or in the brain)

Related Conditions & MeSH terms

• Musculoskeletal Pain
• Occupational Exposure
• Occupational Health
• Physical Capacity
• Work Ability

Intervention

Other:
• Health Examination
The study is a cross-sectional study and therefore there is no intervention. The study consist only of tests, questionnaires and a blood test. See the elements under outcomes measures.

Locations

Country	Name	City	State
Denmark	The Hospital South West Jutland, University hospital of Southern Denmark	Esbjerg

Sponsors (1)

Lead Sponsor	Collaborator
Hospital of South West Jutland

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Work Ability	Measured with Work Ability Index (WAI), which is a questionnaire, measuring seven items to assess the workers work ability	Baseline
Secondary	Height	Measured in centimeters	Baseline
Secondary	Weight	Measured in kilograms	Baseline
Secondary	Body Mass Index (BMI)	Calculated by kg/m^2	Baseline
Secondary	Waist-to-hip ratio	Measured in centimeters between the hip and the waist	Baseline
Secondary	Blood pressure	Both diastolic and systolic	Baseline
Secondary	Pressure Pain Threshold	A part of the quantitative sensory testing battery. Measured with an algometer three times on thenar eminence at the non-dominant hand and at tibialis anterior on the non-dominant leg	Baseline
Secondary	Warm and cold detection threshold	A part of the quantitative sensory testing battery. Measured with a TSA 2001-II machine on thenar eminence at the non-dominant hand. The temperature rises and falls three times each with 1°C/s. The participant press a button, when they feel a change in temperature.	Baseline
Secondary	Heat and cold pain threshold	A part of the quantitative sensory testing battery. Measured with a TSA 2001-II machine on thenar eminence at the non-dominant hand. The temperature rises falls three times each with 1°C/s. The participant press a button, when they detects pain.	Baseline
Secondary	Temporal summation	A part of the quantitative sensory testing battery. Measured with a TSA 2001-II machine. Ten brief repetitive heat pulses at thenar eminence on both hands. There the participant rates the second pain approximately one second after each stimulus.	Baseline
Secondary	Conditioned pain modulation	A part of the quantitative sensory testing battery. Two separate stimuli were used. A test stimulus and a conditioning stimulus. The test stimulus consisted of pressure pain threshold measurements as described above. The test stimulus was performed on the non-dominant hand at the thenar eminence and tibialis anterior before and immediately after the conditioning stimulus, with one minute between the two test sides. The conditioning stimulus was a cold pressor test which consisted of cold water (10°C) immersion of the hand on the dominant side down to the wrist for a duration of two minutes.	Baseline
Secondary	Physical Activity	Measured with The international Physical Activity Questionnaire (IPAQ), which is a 27-item self-reported questionnaire about physical activity for the last seven days at work and in spare time.	Baseline
Secondary	Musculoskeletal pain	Measured with Nordic Musculoskeletal Questionnaire (NMQ). NMQ consist of a generally questionnaire to asses musculoskeletal disorders in nine anatomical region (ex. Shoulder, low back and knee). In addition, NMQ contains special questionnaires for low back, neck and shoulder symptoms to probe these areas more deeply. In this questionnaire, there have been an extension in the special questionnaires to all nine anatomical regions.	Baseline
Secondary	Additionally questions about ergonomic and pain	In addition to the standardized questionnaires described above, an extra questionnaire with further questions about the participant's ergonomics in their work and more generally about their pain on a scale from zero to ten.	Baseline
Secondary	30-seconds sit to stand test	Used to test the strength and endurance in the legs. Its measures how many times the participant can get up from a chair in 30 seconds.	Baseline
Secondary	Balance test	Performed with a one-leg balance test. It measure how low the participant can stand on one leg with the arms on the waist.	Baseline
Secondary	Stair climb test	Measures functional strength, balance and agility. The participant must climb up and down a flight of stairs as quickly as possible.	Baseline
Secondary	Maximal aerobic capacity (VO2 max)	Measured with a sub maximal treadmill exercise test, known as Astrand 6 minute cycle test	Baseline
Secondary	Isokinetic muscle strength in the shoulder	Measured with a Biodex System 4 dynamometer. The dominant shoulder is tested. The participant makes an abduction and adduction as fast and powerful they can. The test is performed three times with 15 seconds rest between the tests.	Baseline
Secondary	Isometric muscle strength in the shoulder	Measured with a Biodex System 4 dynamometer. An isometric contraction in abduction in the dominant shoulder. The participant keeps the tension in 3-5 seconds with 40 seconds break between each test.	Baseline
Secondary	Isokinetic muscle strength in the knee	Measured with a Biodex System 4 dynamometer. The non-dominant knee is tested. The participant makes an extension and flexion as fast and powerful they can. The test is performed three times with 15 seconds rest between the tests.	Baseline
Secondary	Isometric muscle strength in the knee	Measured with a Biodex System 4 dynamometer. An isometric contraction in extension in the non-dominant knee. The participant keeps the tension in 3-5 seconds with 40 seconds break between each test.	Baseline
Secondary	Handgrip strength	Performed with a JAMAR hand dynamometer. The participant press the dominant hand as hard as they can for three to five seconds. The test is performed three times with 15 seconds break between each test.	Baseline
Secondary	Psychosocial work environment	Measured with the Danish Psychosocial Work Environment Questionnaire (DPQ). DPQ is a questionnaire used to evaluate the physical work environment (11). It contains 38 themes regarding to physical work environment within five overall dimensions.	Once after baseline