Clinical Trials Logo
  1. Home
  2. Obstructive Sleep Apnea Syndrome
  3. NCT02522819

Feasibility Evaluation of CPAP in the Treatment of Obstructive Sleep Apnea Synchrone in the Acute Phase of Stroke

Obstructive Sleep Apnea Syndrome Clinical Trial

Official title:
Feasibility Evaluation of Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnea Synchrone in the Acute Phase of Stroke

Clinical Trial Summary

This project is focused on the treatment of obstructive sleep apnea in the acute phase of stroke. Stroke is a frequent pathology with a high morbidity and mortality rate. Although it has now been proved that obstructive sleep apnea syndrome (OSAS) is a risk factor of stroke, on the other hand, there is evidence that 50 to 70% of patients in the acute phase of stroke have obstructive sleep apnea (OSA) based on an apnea-hypopnea index (AHI) of ≥ 10. OSA is associated with worse functional outcomes and higher mortality in the post-stroke period. Profound hemodynamic fluctuations and hypoxia generated by sleep apnea are likely to aggravate cerebral ischemia, particularly in the acute phase of stroke in the potentially reversible ischemic penumbra. Continuous Positive Airway Pressure (CPAP) is the primary treatment for obstructive sleep apnea.

Yet, to our knowledge, there have been very few studies aimed at demonstrating the value of CPAP in the treatment of obstructive sleep apnea in the acute phase of stroke. Only one randomised trial has provided the means to document neurological improvement at mid term (1 month) in a targeted population.

Before undertaking a comparative study evaluating the efficacy of CPAP in the acute phase of ischemic stroke, it is worth evaluating the feasibility and tolerance of introducing CPAP at the very early stage of ischemic stroke. Therefore, the purpose of our study is to evaluate the feasibility of CPAP in the treatment of OSA in the acute phase of ischemic stroke.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02522819
Study type Interventional
Source Centre Hospitalier Universitaire de Saint Etienne
Contact
Status Completed
Phase N/A
Start date October 2011
Completion date November 2014
View Details
See also
  Status Clinical Trial Phase
Withdrawn NCT05164211 - Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children N/A
Active, not recruiting NCT05049928 - m-Rehab OSA : Impact of a Telerehabilitation Program Associated With CPAP on Severity Markers of Obstructive Sleep Apnea Syndrome N/A
Not yet recruiting NCT04538274 - Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use N/A
Completed NCT02967367 - Reliability of Consumer Sleep Trackers in Patients Suffering From Obstructive Sleep Apnea Syndrome N/A
Completed NCT02180672 - Steroids for Pediatric Apnea Research in Kids Phase 3
Recruiting NCT01561677 - Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke. N/A
Completed NCT01808508 - Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome N/A
Completed NCT01193738 - Osteopathy and Obstructive Sleep Apnea Syndrome N/A
Completed NCT01090297 - Continuous Positive Airway Pressure (CPAP) Mode Impact on Clinical Blood Arterial Pressure N/A
Completed NCT00801671 - Russian Study of the Effect of Continuous Positive Airway Pressure (CPAP) in Hypertension Phase 3
Completed NCT00850876 - Heated Humidified Continuous Positive Airway Pressure and Nasal Physiology N/A
Completed NCT02085720 - Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance N/A
Recruiting NCT00874913 - Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS) N/A
Completed NCT00156442 - A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate N/A
Withdrawn NCT00156455 - Sleep Disordered Breathing in Children With Single Ventricle Physiology N/A
Completed NCT00222963 - Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents N/A
Completed NCT01045499 - LAGB as a Treatment for Morbid Obesity in Adolescents N/A
Withdrawn NCT02559427 - SPA Therapy in the Treatment of Sleep Apnea Syndrome N/A
Completed NCT02995837 - Cerebral Blood Flow and Childhood Obstructive Sleep Apnea
Completed NCT01289405 - Phonoaudiologic Therapy Adjunct to Treatment on Patients With Obstructive Sleep Apnea N/A