Impact of Intermittent Hypoxia on the Function of the Phagocytes

Status Recruiting

Clinical Trial Summary

Patients with treatment-naive obstructive sleep apnea (OSA) who need continuous positive airway pressure (CPAP) therapy on clinical basis are included as well as healthy controls without OSA. 15 cc peripheral venous blood is drawn on the date of diagnosis of OSA and 3-6 months after CPAP therapy. Granulocytes are harvested and tested for its function, such as phagocytosis, reactive oxygen species (ROS) production and bacteria-killing ability.

Clinical Trial Description

Patients with treatment-naive obstructive sleep apnea (OSA) who need continuous positive airway pressure (CPAP) therapy on clinical basis are included. Healthy controls without OSA are enrolled, too. 15 cc peripheral venous blood is drawn on the date of diagnosis of OSA and 3-6 months after CPAP therapy (not given to controls). Granulocytes are harvested and tested for its function, such as phagocytosis, reactive oxygen species (ROS) production and bacteria-killing ability. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03618719
Study type	Observational
Source	Taipei Veterans General Hospital, Taiwan
Contact	Kun-Ta Chou, M.D
Phone	+886922407055
Email	ale1371@yahoo.com.tw
Status	Recruiting
Phase
Start date	March 5, 2019
Completion date	July 3, 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05489562` - Use of Intraoral Suction and Its Effects on Obstructive Sleep Apnea	N/A
Recruiting	`NCT05717959` - Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device	N/A
Recruiting	`NCT06008626` - Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea	N/A
Completed	`NCT03940781` - Effects of Rehabilitation for Patients With Obstructive Sleep Apnea	N/A
Completed	`NCT03122639` - Endothelial Function in Obstructive Sleep Apnea	Early Phase 1
Recruiting	`NCT05289063` - Vascular Endothelial Dysfunction in Sleep Apnea	Phase 1
Not yet recruiting	`NCT05268471` - Cost-effectiveness Analysis and Conditional Response to the Effect of Positional Devices in Obstructive Sleep Apnea	N/A
Active, not recruiting	`NCT04864652` - Safety and Dosing Study of the CHILLS Cryotherapy for the Treatment of OSA	N/A
Enrolling by invitation	`NCT05433883` - The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness	N/A
Recruiting	`NCT06103630` - Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device	N/A
Recruiting	`NCT06283095` - Management of Obstructive Sleep Apnea Syndrome by Expansion Palatoplasty	N/A
Completed	`NCT03156283` - SleepWell24: An Innovative Smartphone Application to Improve PAP Adherence	N/A
Completed	`NCT03362385` - OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients
Recruiting	`NCT06447818` - Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome
Completed	`NCT04643782` - Comparative Study of the ANNE™ One System to Diagnose Obstructive Sleep Apnea	N/A
Recruiting	`NCT03463785` - Does Race Make a Difference in Obstructive Sleep Apnea?
Completed	`NCT03048604` - BiLAteral Hypoglossal Nerve Stimulation for Treatment of Obstructive Sleep Apnoea (BLAST OSA)	N/A
Recruiting	`NCT05290350` - Long COVID-19 Fatigue and Obstructive Sleep Apnea
Recruiting	`NCT05739617` - Comprehensive Respiratory Training Exercise Program in Obstructive Sleep Apnea	N/A
Completed	`NCT03980158` - Change in Tongue Strength and Fatigue After Upper Airway Stimulation Therapy