Obstetric Pain Clinical Trial
Official title:
The Transversus Abdominis Plane Block
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia. The hypothesis that this technique has effect to postoperative analgesia for cesarean section with general anesthesia and it could reduce 50% of total morphine consumption during 24 hours after surgery.
This is a randomized, controlled, no-blind clinical trial. The investigators selected 60 cases, who were cesarean section under general anesthesia, age from18 years, and American Society Anesthesiologists (ASA) classification was from II-III. The cases of acute fetal impairment, local anesthesia contraindication, tolerance opioids, liver failure, renal failure, and spinal anesthesia failure were excluded. All cases were randomized assigned two groups: the TAP block group (T group) and controlled group (C group). Each group has 30 cases. The TAP block was performed under the ultrasound guidance with 0.25% of ropivacaine 20 ml each side. The both groups was treated postoperative analgesia with intravenous morphine to patients controlled analgesia (PCA). The primary outcome was total morphine consumption during 24 hours after surgery. The secondary outcomes were the time of required the first dose of morphine, pain score, the complications of TAP block, the side effects of morphine, and satisfaction score of participants. Data was described and analyzed with SPSS 25.0. The sample size was calculated with the hypothesis that TAP block could reduce 50% of dose morphine during 24 hours after surgery, 80% of power, 10% of loss, and 0.05 of alpha error. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04037085 -
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
|
Phase 2 | |
Recruiting |
NCT03623256 -
Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Analgesia
|
Phase 4 | |
Completed |
NCT04443569 -
Lidocaine Patches After Cesarean Section
|
Phase 3 | |
Completed |
NCT03502642 -
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
|
Phase 4 | |
Completed |
NCT03596333 -
Color Doppler Ultrasound to Locate Needle in Labor Epidural
|
||
Recruiting |
NCT02427139 -
ANSiStim Study for Active Labor Pain
|
N/A | |
Not yet recruiting |
NCT06304246 -
The Relationship Between Preoperative Serum Asprosin Level and Postoperative Analgesic Consumption in Patients Undergoing Caesarean Section
|
||
Completed |
NCT06429111 -
Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
|
||
Not yet recruiting |
NCT05196256 -
Study Comparing Dural Puncture Epidural With Epidural and Combined Spinal Epidural Anesthesia for Obstetric Analgesia.
|
Phase 3 | |
Not yet recruiting |
NCT04983511 -
Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population
|
N/A | |
Completed |
NCT02244086 -
Analgesic Efficacy of Two Concentrations of Bupivacaine in Women in Labor
|
Phase 4 | |
Completed |
NCT03495531 -
Virtual Reality in Obstetric Patients
|
N/A | |
Completed |
NCT00361712 -
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
|
Phase 4 | |
Terminated |
NCT04011098 -
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
|
Phase 1 | |
Not yet recruiting |
NCT06055686 -
The Use of Electrical Stimulation for Determination of Epidural Catheter Placement
|
N/A | |
Withdrawn |
NCT02857465 -
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
|
Phase 3 | |
Completed |
NCT02340806 -
Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
|
N/A | |
Recruiting |
NCT04728048 -
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
|
N/A | |
Completed |
NCT04637386 -
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
|
N/A | |
Completed |
NCT05447455 -
TAP Block vs LAWI for Analgesia Post-cesarean Section
|
N/A |