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Obstetric Complication clinical trials

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NCT ID: NCT04894136 Completed - Clinical trials for Obstetric Complication

Reproductive and Obstetric Outcomes in TESE-ICSI Cycles for Azoospermia

AZOOCOMES
Start date: January 1, 2001
Phase:
Study type: Observational

A comparison of reproductive and obstetrical outcomes is retrospectively performed among couples that underwent ICSI-TESE cycles for obstructive and non obstructive azoospermia between January 2001 and December 2019.

NCT ID: NCT04852237 Completed - Clinical trials for Obstetric Complication

Is the Lack of Prior Exposure to Sperm Antigens Associated With Worse Neonatal and Maternal Outcomes?

Start date: January 1, 2010
Phase:
Study type: Observational

The objective of this study is to determine if the lack of exposure to sperm antigens is associated with worse maternal and neonatal outcomes in pregnancies obtained after ICSI (intracytoplasmic sperm injection)-TESE (testicular sperm extraction) for obstructive azoospermia. The primary outcomes that will be investigated include: - Maternal outcomes: live birth rate (LBR), abortion rate, and the rate of the main obstetrics complication, such as pre-eclampsia, gestational hypertension and diabetes mellitus. - Neonatal outcomes: gestational age, prematurity rate, birth weight, sex ratio, 1- and 5-min APGAR, birth defects.

NCT ID: NCT04699578 Recruiting - Covid19 Clinical Trials

COVID-19 Infection and Fetal-neonatal Outcomes

Start date: December 28, 2020
Phase:
Study type: Observational

COVID-19, the coronavirus responsible for the pandemic that began at the end of 2019 in China, spreads through respiratory droplets and direct contact. The most common symptoms of the disease include fever, cough, asthenia or myalgia, wheezing and headache, and the most serious complication is acute respiratory distress syndrome (ARDS). The new coronavirus has continued to spread to multiple countries and continents so much so that the epidemic was declared a Public Health Emergency of International Interest (PHEIC) by the World Health Organization (WHO) on January 30, 2020. In the first phase of emergency worldwide, characterized by high morbidity and mortality, scientific interest has been mainly directed to the study of the transmission mechanisms of the infection, diagnostic tools and therapies for ARDS, especially in elderly and co-morbid patients. Interest has rapidly spread to other categories of patients and in particular to pregnancy, on which the virus could impact in different ways, with consequences for both the mother and the fetus. A recent systematic review that included all published reports on Coronaviruses (COVID-19, SARS, and MERS) in pregnancy showed that preterm delivery is the most frequently reported adverse event in these women, and that COVID-19 is associated with an increased risk of preeclampsia and caesarean section. Nonetheless, the limited sample size, the main inclusion of cases reported for acute respiratory symptoms, the lack of information on previous pathologies potentially capable of complicating pregnancy, do not allow for the extrapolation of strong evidence on the course of infection in pregnancy. Therefore, the current status of the scientific literature does not allow for general and wide-ranging implications. THe investigators therefore believe it is particularly useful to investigate maternal and fetal outcomes in this new broader scenario, including all pregnancies associated with asymptomatic or symptomatic SARS-CoV-2 infection, found in any gestational period, in order to evaluate in a "real world scenario" "Actual rates of maternal-fetal and neonatal adverse events

NCT ID: NCT04664660 Recruiting - Endometriosis Clinical Trials

Endometriosis and Obstetric Outcomes

Start date: March 10, 2020
Phase:
Study type: Observational

The purpose of this study is to assess if endometriosis can be considered a risk factor for adverse obstetric and delivery outcomes

NCT ID: NCT04536753 Completed - Ultrasound Clinical Trials

The Utility of Customised Growth Charts for Identifying Macrosomia and the Effect of Intervention

Start date: January 1, 2018
Phase:
Study type: Observational

Best management of suspected large for gestational age (LGA) fetuses is unclear. In some hospitals women with an LGA fetus by customised growth charts are are offered earlier induction. This study aimed to examine scan accuracy for this group and the outcome with intervention.

NCT ID: NCT04483986 Active, not recruiting - Muscle Injury Clinical Trials

Does Rectus Re-approximation Cause Adhesion After Cesarean Section?

Start date: May 25, 2020
Phase: N/A
Study type: Interventional

Rectus re-approximation and periton closure are not the obligatory steps during cesarean section. These steps are due to surgeon's preference. However, there is lack of knowledge about the relation of rectus muscle re-approximation and adhesion formation. We are going to study the rectus muscle stiffness by share-wave elastosonography.

NCT ID: NCT04399174 Completed - Clinical trials for Obstetric Complication

Placental Vasculature for Prediction of Recurrent Fetal Growth Restriction

Start date: December 15, 2016
Phase:
Study type: Observational

: In this Prospective longitudinal observational study, two hundred pregnant women with singleton pregnancy from 11 up to 13 weeks with history of intrauterine growth restriction in a previous pregnancy underwent ultrasound assessment of gestational age , ultrasound assessment of uterine artery pulsatility index, placental volume by 3D ultrasound and placental vascularization by 3D power Doppler (3DPD).

NCT ID: NCT04181840 Completed - Clinical trials for Obstetric Complication

Impedance Spectroscopy for Obstetric Anal Sphincter Injuries Detection

Start date: October 15, 2019
Phase: N/A
Study type: Interventional

The main purpose of the study is to evaluate the effectiveness and safety of the impedance spectroscopy device prototype in the detection of anal sphincter injuries in women in the early postpartum period. The study is prospective. The study group comprises up to 56 patients; up to 16 weeks from a natural delivery. The planned participation of each patient in the study is up to 4 weeks and two visits will take place at that time. After obtaining written consent, at the first visit (V1) each patient will undergo a physical examination (both proctological and gynecological examination), blood samples for laboratory tests and stool samples for calprotectin concentration assessment will be collected. The presence of clinical symptoms of both gas and stool incontinence will be assessed during the visit with the use of Wexner's scale. Then, the dates of two reference tests will be planned: Trans-rectal USG and Recto-anal manometry which will be performed as part of the V1 visit within a period not exceeding 27 days. The V2 visit, which will also be the final visit, will include a reassessment of the patient's general condition, recording the values of basic vital parameters, subjective and physical examination, and then the doctor conducting the examination will finally determine the extent of sphincter damage, present the patient with therapeutic options and decide on the treatment or rehabilitation of sphincter. During the visits, all adverse events will also be monitored, both those reported by patients and those related to the examined diagnostic device.

NCT ID: NCT03856307 Completed - Clinical trials for Obstetric Complication

Reliability of Simple Sonographic Findings Acquired With Hand-held Apparatuses to Inform Obstetric Diagnosis

Start date: March 1, 2019
Phase:
Study type: Observational [Patient Registry]

the study aims to assess the reliability of ultrasound findings measured by hand held ultrasound probes used by operators with variable experience in a low resource hospital.

NCT ID: NCT03828630 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Lung Ultrasound to Detect Pulmonary Complications in Critically Ill Parturients

LUSIP
Start date: July 8, 2018
Phase:
Study type: Observational

This study aims at describing the frequency, timing and type of pulmonary complications detected with lung ultrasound in critically-ill parturients in admitted to a high-dependency unit in Freetown, Sierra Leone.