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Clinical Trial Summary

This study will conduct the development and preliminary evaluation of Cognitive Bias Modification for Interpretation (CBM-I) and Approach Avoidance Training (AAT) as augmentations to treatment as usual for OCD and related disorders. CBM-I refers to computerized interventions designed to directly manipulate interpretation bias through repeated practice on a training task, thereby inducing cognitive changes in a relatively automatic or implicit manner. In AAT, automatic approach tendencies toward feared stimuli are re-trained. Specifically, this study will examine the feasibility, acceptability, and clinical outcomes associated with CBM-I and AAT. Adults with obsessive compulsive disorder (OCD) and related disorders will be recruited from a treatment program for these disorders and participants will be randomly assigned to either receive: 1) eight sessions of CBM-I or eight sessions of psychoeducation as a control condition, or 2) AAT or eight sessions of an inactive (sham) version of the AAT training.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03799419
Study type Interventional
Source Mclean Hospital
Contact Martha Falkenstein
Phone 617-855-4424
Email mfalkenstein@mclean.harvard.edu
Status Recruiting
Phase N/A
Start date April 1, 2019
Completion date December 2024

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