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TMS-induced Plasticity Improving Cognitive Control in OCD — TIPICCO  

Obsessive-Compulsive Disorder Clinical Trial

Official title:
Transcranial Magnetic Stimulation (TMS)-Induced Plasticity Improving Cognitive Control in Obsessive-compulsive Disorder (OCD)

Clinical Trial Summary

Repetitive transcranial magnetic stimulation (rTMS) has been shown in several previous clinical trials to be an effective treatment for obsessive-compulsive disorder (OCD). However, the neural working mechanisms of rTMS in OCD are unknown, and the optimal stimulation sites have not yet been established. Our study aims to compare the clinical and neurobiological effects of three different rTMS stimulation protocols in OCD patients. 8 weeks of rTMS therapy will be delivered in combination with cognitive behavioural therapy. Multimodal neuroimaging will be carried out before and after treatment in order to demonstrate the neurobiological effects of the therapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03667807
Study type Interventional
Source Amsterdam UMC, location VUmc
Contact
Status Active, not recruiting
Phase N/A
Start date May 8, 2019
Completion date July 1, 2023
View Details
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