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Safety and Effectiveness of Capsulotomy in Refractory OCD

Obsessive-Compulsive Disorder Clinical Trial

Official title:
Safety and Effectiveness of Capsulotomy in Refractory Obsessive-Compulsive Disorder

Clinical Trial Summary

Obsessive-compulsive disorder (OCD) is a severely disabling psychiatric disorder with a worldwide lifetime prevalence of 2-3% (Islam et al., 2015).Despite the efficacy of pharmacological and behavioural treatment methods for most OCD patients, roughly one third do not demonstrate significant symptom improvement, even after aggressive treatment (Foa et al, 2007). The effectiveness of neurosurgical treatment methods (including ablative surgery) for those with severely disabling treatment resistant OCD is substantiated by clinical research (Greenberg, Rauch & Haber, 2010). The brain target of this procedure is usually the area between the anterior and middle third of the anterior limb of the internal capsule.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02375152
Study type Interventional
Source Ruijin Hospital
Contact ChenCheng Zhang, MD
Email zhangchencheng@hotmail.com
Status Recruiting
Phase Phase 2/Phase 3
Start date April 2015
Completion date December 2018
View Details
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