Obsessive-Compulsive Disorder Clinical Trial
Official title:
Neurofeedback of Activity in the Orbitofrontal Cortex for OCD
The aim of this study is to train patients with obsessive-compulsive disorder to control a region of their brain that has been associated with their symptoms. Patients in the experimental group will be given direct feedback regarding activity in this brain area while they are undergoing functional magnetic resonance imaging (fMRI) scanning, and will try to learn to control activity in the region during these feedback sessions. A separate group of patients will be given a control form of feedback that we do not believe can have clinical benefits. Our primary hypothesis is that the neurofeedback training will reduce OCD symptoms more than the control feedback.
Original study design recruiting controls who were matched to the experimental group was changed to a randomized design prior to enrollment of the first participant. ;
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