Obsessive Compulsive Disorder Clinical Trial
Official title:
Attention Training for Childhood Obsessive Compulsive Disorder: An Open Case Series
Pediatric Obsessive Compulsive Disorder (OCD) is a chronic, impairing condition that accrues
significant concurrent and long-term risk to affected youth. Although empirically supported
psychosocial and pharmacological treatments for OCD exist, many children and their families
are not able to adequately access these treatments or derive only partial benefit from them.
Such findings highlight the importance of developing more effective treatment options which
have the potential to be widely accessible to OCD youth.
The investigators are proposing to test a computerized attention modification program, AMP,
in six youth with OCD in an open case series to gather information regarding protocol
acceptability, feasibility and preliminary efficacy. This phase includes the development and
refinement of stimuli selection procedures, behavior avoidance task, EEG protocol, and AMP
parameters for use with children.
Following ascertainment of study eligibility, participants will undergo a baseline
assessment consisting of a clinical interview, neurocognitive assessments, EEG, attention
bias assessment, and self report questionnaires. Study participants will then receive 12
sessions of AMP treatment over the course of three weeks. All youngsters and their families
will be reassessed at treatment endpoint (week 4). Participation will take a total of about
24 hours over the course of six weeks. Participants who are treatment responders may be
asked to return approximately 3 months after completing treatment for a follow-up
assessment.
Preliminary hypotheses: 1) AMP will be acceptable to youth and families and feasible to
administer; 2) Youth receiving AMP will demonstrate decreases in threat bias and OCD symptom
severity.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04631042 -
Developing Brain, Impulsivity and Compulsivity
|
||
Completed |
NCT02855580 -
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
|
||
Completed |
NCT02229903 -
An Evaluation of the Safety and Efficacy of the dTMS Treatment for OCD
|
N/A | |
Completed |
NCT02202915 -
CBT for Pediatric OCD: Community Training Pilot
|
N/A | |
Completed |
NCT01794156 -
Evaluation of a Cognitive Therapy (Inference-based-therapy) for the Treatment of Obsessional Compulsive Disorder
|
N/A | |
Completed |
NCT02089984 -
Web Based Therapist Training on Cognitive Behavior Therapy for Anxiety Disorders
|
N/A | |
Completed |
NCT01348529 -
Internet Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
|
N/A | |
Recruiting |
NCT00965211 -
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome
|
N/A | |
Completed |
NCT01172873 -
D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD
|
N/A | |
Not yet recruiting |
NCT00743834 -
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
|
Phase 4 | |
Completed |
NCT00723060 -
Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder
|
Phase 4 | |
Completed |
NCT02421315 -
Overlapping Neural Circuits in Pediatric OCD
|
N/A | |
Completed |
NCT01981317 -
Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder
|
N/A | |
Completed |
NCT02194075 -
Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder
|
Phase 4 | |
Completed |
NCT01686087 -
Attaining and Maintaining Wellness in Obsessive-compulsive Disorder
|
N/A | |
Terminated |
NCT00997087 -
A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder
|
Phase 2 | |
Completed |
NCT01331876 -
Modification of Cerebral Activity of Obsessive Compulsive Disorder (OCD) Patients During Cognitive and Behavioral Therapy
|
N/A | |
Completed |
NCT00533806 -
Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder
|
Phase 3 | |
Completed |
NCT00517244 -
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
|
N/A | |
Completed |
NCT00169377 -
Subthalamic Nucleus (STN) Stimulation and Obsessive-Compulsive Disorder (OCD)
|
Phase 1/Phase 2 |