Obsessive Compulsive Disorder Clinical Trial
Official title:
Attention Training for Childhood Obsessive Compulsive Disorder: An Open Case Series
Pediatric Obsessive Compulsive Disorder (OCD) is a chronic, impairing condition that accrues
significant concurrent and long-term risk to affected youth. Although empirically supported
psychosocial and pharmacological treatments for OCD exist, many children and their families
are not able to adequately access these treatments or derive only partial benefit from them.
Such findings highlight the importance of developing more effective treatment options which
have the potential to be widely accessible to OCD youth.
The investigators are proposing to test a computerized attention modification program, AMP,
in six youth with OCD in an open case series to gather information regarding protocol
acceptability, feasibility and preliminary efficacy. This phase includes the development and
refinement of stimuli selection procedures, behavior avoidance task, EEG protocol, and AMP
parameters for use with children.
Following ascertainment of study eligibility, participants will undergo a baseline
assessment consisting of a clinical interview, neurocognitive assessments, EEG, attention
bias assessment, and self report questionnaires. Study participants will then receive 12
sessions of AMP treatment over the course of three weeks. All youngsters and their families
will be reassessed at treatment endpoint (week 4). Participation will take a total of about
24 hours over the course of six weeks. Participants who are treatment responders may be
asked to return approximately 3 months after completing treatment for a follow-up
assessment.
Preliminary hypotheses: 1) AMP will be acceptable to youth and families and feasible to
administer; 2) Youth receiving AMP will demonstrate decreases in threat bias and OCD symptom
severity.
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