Obese Clinical Trial
Official title:
Respiratory Variations in Diameters of the Inferior Vena Cava and the Internal Jugular Vein to Assess Blood Withdrawal in Patients With Dysmetabolic Hyperferritinemia
OBJECTIVES: To investigate whether respiratory variations of the inferior vena cava (ΔIVC)
and internal jugular vein (ΔIJV) diameters during standardized breathing (ΔIVCST and ΔIJVST)
increase after a therapeutic bleeding in spontaneously breathing and obese patients with
dysmetabolic hyperferricemia.
DESIGN: Prospective, monocentric study in the EFS Nord-de-France blood center.
PATIENTS: Obese patients with dysmetabolic hyperferricemia undergoing a therapeutic
bleeding.
INTERVENTIONS: The investigators performed ultrasound measures and collected clinical
parameters before and after a therapeutic bleeding, during a standardized respiratory
maneuver.
MAIN OUTCOME AND MEASURES: The primary endpoint was the ΔIVCST change induced by a 300 to
500ml therapeutic bleeding. The investigators measured the minimal and maximal IVC and IJV
diameters during a standardized respiratory maneuver. ΔIVCST and ΔIJVST were calculated as
follows: [(maximal diameter - minimal diameter)/maximal diameter].100.
n/a
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