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Clinical Trial Summary

This study will examine the impact of creatine supplementation on muscle function and cognitive performance in young and older subjects.


Clinical Trial Description

This is a randomised, double-blind study of the effects of creatine supplementation on muscle energetics and cognitive function, using 31P-MRS and fMRI. 31P-MRS data will be acquired continuously during exercise phase and in the post-exercise metabolic recovery phase. Participants will undergo a fMRI scan of the brain to record changes in the blood oxygen level dependent (BOLD) signal during a series of cognitive tests. In addition, participants will undergo a resting state BOLD scan and a structural MRI scan for localization of brain regions. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02058654
Study type Interventional
Source GlaxoSmithKline
Contact
Status Completed
Phase Phase 1
Start date December 1, 2013
Completion date June 24, 2014

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