Nutritional Rickets Clinical Trial
Official title:
Role of Calcium And Vitamin D In Nutritional Rickets And It's Management
Rickets, a common nutritional disorder, is usually considered to be due to vitamin D
deficiency. However, in the last few decades many studies have shown that in tropical
countries, with abundance of sunshine, calcium deficiency may play a more important role in
the causation of rickets. Studies from adults in India have also shown that calcium intake
of our population is much below the recommended allowance. The calcium deficiency gets
compounded by the high level of phytates in the conventional vegetarian diet consumed by the
majority of the population. There are few studies on children in India / other Asian
countries on assessment of dietary calcium intake.
However, recent studies from many nations of the world have also shown a wide spread
prevalence of vitamin D deficiency in adolescent and adult population. A study done at our
own hospital has shown a high prevalence of vitamin D deficiency in lactating mothers and
their infants.
Since both Calcium and Vitamin D deficiency are likely to be present in children, it is not
clear what plays a more important role in the etiology of rickets in India or other Asian
countries.
The present study is therefore planned with the following objectives:
1. To study the dietary calcium intake, sun exposure and serum vitamin D levels in
children with and without rickets.
2. To compare the role of Calcium Carbonate, Vitamin D and a combination of the two in the
treatment of nutritional rickets.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05310760 -
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
|
Phase 2/Phase 3 | |
| Completed |
NCT00949832 -
Vitamin D and Genetics in Nutritional Rickets
|
Phase 4 |