Nutritional Requirements Clinical Trial
Official title:
Study on Physiologic Requirement and Dietary Recommended Nutrient
NCT number | NCT04419103 |
Other study ID # | NSFC-81803223 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | July 1, 2019 |
Est. completion date | December 1, 2021 |
Verified date | November 2022 |
Source | Tianjin Medical University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Iodine is one of essential micronutrient for human, both iodine deficiency and excess will be harmful for human health. Children is the susceptible population to iodine nutrition, and studies show that even mild iodine deficiency would affect the growth and development of children, so it is urgent to identify the dietary recommended nutrient intake (RNI) of iodine for children to guide children scientifically and safely supplement iodine. There are few studies about the dietary recommended nutrient intake (RNI) of iodine in children, and present data are old and outdated.
Status | Completed |
Enrollment | 600 |
Est. completion date | December 1, 2021 |
Est. primary completion date | October 1, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 7 Years to 11 Years |
Eligibility | Inclusion Criteria: Normal body mass index and thyroid function have not been treated for thyroid disease have not used amiodarone and other drugs (including iodine supplements) during the investigation have no major diseases and family history have lived in the local area for more than 5 years Exclusion Criteria: Long-term low-protein long-term low-heat energy malnutrition |
Country | Name | City | State |
---|---|---|---|
China | Shandong Institute for Endemic Disease Control and Research | Dezhou | Shandong |
Lead Sponsor | Collaborator |
---|---|
Tianjin Medical University | Shandong Institute for Endemic Disease Control and Research |
China,
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* Note: There are 21 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | urinary iodine concentration | µg/L | 2 weeks | |
Primary | free triiodothyronine | pmol/L | 2 weeks | |
Primary | water iodine intake | µg/day | 2 weeks | |
Primary | diet iodine intake | µg/day | 2 weeks | |
Primary | salt iodine concentration | µg/L | 2 weeks | |
Primary | free thyroxine | pmol/L | 2 weeks | |
Primary | thyroid-stimulating hormone | mIU/L | 2 weeks | |
Primary | thyroperoxidase antibody | IU/mL | 2 weeks | |
Primary | thyroglobulin antibody | IU/mL | 2 weeks | |
Primary | urinary iodine excretion | µg/day | 2 weeks | |
Primary | fecal iodine excretion | µg/day | 2 weeks |
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