NSCLC Clinical Trial
Official title:
Efficacy and Safety Study of Anlotinib With Pembrolizumab in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Non-small Cell Lung Cancer
The purpose of this study is to assess the safety and efficacy of Anlotinib (AL3818) combined
with pembrolizumab (MK-3475) in treatment-naïve adults with no prior systemic therapy for
advanced non-small cell lung cancer (NSCLC) whose tumors have a programmed cell death-ligand
1 (PD-L1) Tumor Proportion Score (TPS) greater than or equal to 1%.
The primary study hypotheses is that the combination of Anlotinib and pembrolizumab is
superior to pembrolizumab alone(historical data) as assessed by Progression-free Survival
(PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1).
n/a
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