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Clinical Trial Summary

This phase Ib study will investigate dose limiting toxicity (DLT) and maximum tolerated dose (MTD) of afatinib and ruxolitinib combination therapy, based on the preclinical data that inhibition of IL-6R/JAK1 signal transmission pathway will increase sensitivity to afatinib.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02145637
Study type Interventional
Source Yonsei University
Contact
Status Completed
Phase Phase 1
Start date May 7, 2015
Completion date November 9, 2017

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