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Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status — ADEPPT  

NSCLC Stage IV Clinical Trial

Official title:
A Multicentre, Single-arm Phase II Trial of Adagrasib in Patients With KRASG12C-mutant NSCLC, Including the Elderly (≥70 Years) or Patients With Poor Performance Status

Clinical Trial Summary

ADEPPT is an international, multicentre, single-arm phase II trial. The protocol treatment consists of adagrasib, which is administered at a dose of 600 mg orally, twice daily until progression or unacceptable toxicity.The primary objective of this trial is to assess the clinical efficacy of adagrasib treatment, in terms of objective response, in patients with KRASG12C-mutant NSCLC, including the elderly (≥70 years) or patients with poor performance status (ECOG PS=2).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05673187
Study type Interventional
Source ETOP IBCSG Partners Foundation
Contact Heidi Roschitzki, PhD
Phone +41 31 511 94 00
Email heidi.roschitzki@etop.ibcsg.org
Status Recruiting
Phase Phase 2
Start date June 12, 2023
Completion date March 1, 2026
View Details
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