Clinical Trials Logo

Clinical Trial Summary

Current study aimed to explore the effect of high PEEP during noninvasive ventilation among hypoxemic patients with acute respiratory failure.


Clinical Trial Description

This was a 1:1 randomized control trial to explore the effect of high versus low PEEP in noninvasive ventilation hypoxemic patients with acute respiratory failure. Several ICUs in China performed this study. In the high PEEP group, the PEEP maintained at 10-15 cmH2O, the inspiratory pressure maintained at 15-20 cmH2O. In the low PEEP group, the PEEP maintained at 5 cmH2O, the inspiratory pressure maintained at 10-20 cmH2O. The primary outcome was incidence of noninvasive ventilation failrue. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05193786
Study type Interventional
Source Chongqing Medical University
Contact Jun Duan, Dr.
Phone +8615023077940
Email duanjun412589@163.com
Status Recruiting
Phase N/A
Start date January 1, 2022
Completion date December 30, 2025

See also
  Status Clinical Trial Phase
Completed NCT02845076 - Weaning From Noninvasive Ventilation N/A
Recruiting NCT05008211 - Information-Motivation-Behavioral Skills Model-based Intervention to Domiciliary Non-invasive Ventilation of Patients N/A
Completed NCT03250416 - Management of Noninvasive Ventilation in Hypoxemic Patients
Not yet recruiting NCT03687385 - The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class Patients N/A
Not yet recruiting NCT03687424 - Can High-flow Nasal Oxygenation Improve Oxygen Saturation During Analgo-sedation in Obese Adults? N/A
Recruiting NCT01791335 - NIV and Glottis-diaphragm Synchrony N/A
Recruiting NCT04165382 - Development, Implementation and Evaluation of a Clinical Practice Guideline for Care of Preterm Infants Receiving Non-invasive Ventilation (NIV) N/A
Completed NCT04912544 - Facilitating Patient Communication During Noninvasive Ventilation N/A
Active, not recruiting NCT03499470 - Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV N/A
Not yet recruiting NCT05964244 - Impact of Noninvasive With Expiratory Washout on Respiratory Rate of Patients With Acute Hypercapnic Respiratory Failure N/A
Recruiting NCT03053973 - The Effects of Nocturnal Non-invasive Ventilation in Stable COPD N/A
Terminated NCT04413643 - NIV for COPD: Hospital to Home N/A
Completed NCT03151317 - Effects of a Therapeutic Education Program on Treatment Adherence Among Patients Prescribed At-home CPAP or At-home NIV
Completed NCT03607357 - High Flow Nasal Oxygen and Acute Left Heart Failure N/A
Withdrawn NCT02615834 - Chest Pressure for Intubated Peds Patients N/A
Not yet recruiting NCT02383719 - Mask Comfort Feasibility N/A
Not yet recruiting NCT06260202 - Nutrition Under Noninvasive Ventilation
Completed NCT03876873 - Effect of Head Rotation on Efficacy of Face Mask Ventilation in Anesthetized Obese (BMI ≥ 35) Adults N/A
Completed NCT02267291 - Impact of Non-invasive Positive Pressure Ventilation on Cardiac Function and Echocardiographic Parameters N/A
Not yet recruiting NCT04904484 - A Safety Assessment of the iZephyr Hood for NIV in COVID-19 Patients N/A