Effect of Lighting Supplementation on Daytime Cognition

Non-visual Effects of Light Clinical Trial

Official title:

The Effect of Lighting Supplementation on Cognitive Task Performance During the Day

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04745312
• Other study ID #: 2019P000900
• Secondary ID: 2020A011565
• Status: Active, not recruiting
• Phase: N/A
• Start date: March 1, 2021
• Est. completion date: March 1, 2022

Study information

• Verified date: February 2022
• Source: Brigham and Women's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 16
• Est. completion date: March 1, 2022
• Est. primary completion date: March 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Aged between 18-30 years;

• Healthy (no medical, psychiatric or sleep disorders;

• Non-smoking for at least 6 months;

• Body Mass Index of >18 or <30 kg/m2;

• Able to maintain 7-hour consistent sleep schedule during the study

• Able to refrain from caffeine, alcohol, medication and supplements during the study

Exclusion Criteria:

• History of alcohol or substance abuse;

• positive result on drugs of abuse urine toxicology;

• Current or past history of sleep disorders, including but not limited to obstructive sleep apnea, narcolepsy, insomnia, or any significant sleep complaint

• Psychiatric disorder, or first degree relative with a psychiatric disorder

• Recent acute or chronic medical disorder

• Use of drugs or medication (birth control OK) likely to affect sleep, alertness or light sensitivity, as determined by the investigators

• Visual disorder, including but not limited to color blindness, or family history of glaucoma

• Pregnancy or lactation

• Shift work (> 2 nights / week in the last 3 months and not during the study)

• Transmeridian travel (2 or more time zones) in the past 3 months

• Any other reason as determine by the Principal Investigator

Related Conditions & MeSH terms

• Non-visual Effects of Light

Intervention

Device:
• Visible light
Ambient room lighting will be supplemented with additional light from a task lamp.

Locations

Country	Name	City	State
United States	Brigham and Women's Hospital	Boston	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
Brigham and Women's Hospital

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Vigilance	Reaction time and lapses on the Psychomotor Vigilance Task	8 hour light exposure
Other	Subjective sleepiness	Subjective sleepiness assessed by the Karolinska Sleepiness Scale - Scale from 1-9 where higher scores indicate greater sleepiness	8 hour light exposure
Other	Memory recall	Percentage of correctly recalled words on a paired associates task	8 hour light exposure
Other	Psychological distress	Total score on the Profile of Mood States (POMS)	8 hour light exposure
Other	Affect	Positive and negative affect scores assessed by the PANAS	8 hour light exposure
Primary	Working memory	Percent correct responses on a 2-minute mental arithmetic task	8 hour light exposure
Secondary	Procedural learning	Percent change in the number of correct sequences on the Motor Sequence Task	8 hour light exposure