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Clinical Trial Summary

This is a multicenter, randomized, open label, phase III study.


Clinical Trial Description

This is a multicenter, randomized, open label, phase III study assessing the efficacy and safety of Almonertinib combined with or without chemotherapy as an adjuvant treatment in patients with epidermal growth factor receptor (EGFR) mutation positive stage II-IIIA non-squamous NSCLC following complete tumour resection: Eligible patients will be randomized to receive either Almonertinib alone (110mg, po, once daily) or Almonertinib (110mg, po, once daily) plus pemetrexed (500mg/m2, iv) and cisplatin (500mg/m2, iv) or pemetrexed (500mg/m2, iv) plus cisplatin (500mg/m2, iv) in a 3:2:1 ratio. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04762459
Study type Interventional
Source Chinese Academy of Medical Sciences
Contact
Status Enrolling by invitation
Phase Phase 3
Start date August 1, 2021
Completion date May 2029

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