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Clinical Trial Summary

The study is designed as a non-randomized Phase 2 clinical intervention study. The study will include patients with disseminated Non-Small Cell Lung Carcinoma (NSCLC) which are eligible for first line of systemic treatment with immune checkpoint inhibitors and platinum-based chemotherapy (PDL1 less than 50%). Patients will receive palliative radiotherapy to multiple sites (2 to 5 sites) prior to systemic treatment. Results of treatment will be compared to historical cohort of patients treated only with systemic therapy.


Clinical Trial Description

The primary objective is to investigate efficacy of radiation therapy before the first line of systemic therapy with immune checkpoint inhibitors and platinum-based chemotherapy in metastatic NSCLC (PDL1 less than 50%). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05440916
Study type Interventional
Source University Medical Centre Maribor
Contact Tanja Žnidaric
Phone +386(0)23211917
Email tanja.znidaric@gmail.com
Status Recruiting
Phase Phase 2
Start date July 14, 2022
Completion date December 31, 2025

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