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Neoadjuvant/Adjuvant Pembrolizumab Plus Chemotherapy — NeoP  

Non Small Cell Lung Cancer Clinical Trial

Official title:
A Prospective, Single-arm Phaseâ…¡Trial of Neoadjuvant/Adjuvant Pembrolizumab Plus Platinum-doublet Chemotherapy (Chemo) in IIa-IIIb NSCLC

Clinical Trial Summary

A phase II, single-arm, open-label study evaluating feasibility, safety and efficacy of combined chemotherapy and pembrolizumab as neoadjuvant/adjuvant therapy in stage IIa-IIIB NSCLC adult patients followed by adjuvant PD-(L)1 inhibitor treatment for up to 1 year

Clinical Trial Description

Two to four cycles of neoadjuvant chemotherapy in combination with pembrolizumab will be administered before surgery, followed by another one to two cycles of chemotherapy plus pembrolizumab after surgery (4 cycles neoadjuvant/adjuvant chemotherapy in total ) then use pembrolizumab monotherapy for up to 1 year. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05383716
Study type Interventional
Source Peking Union Medical College Hospital
Contact
Status Active, not recruiting
Phase Phase 2
Start date July 1, 2022
Completion date December 2027
View Details
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