Non-small-cell Lung Cancer Clinical Trial
Official title:
Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients
Cancer is one of the leading health issues in this country and worldwide. Angiogenesis is an
essential process for tumoral growth and metastasis. This process is dependent on the
balance between angiogenic factors and antiangiogenic factors. Muscle wasting has been
associated with myostatin overexpression in cancer. Exercise training can depress tumor
growth and suppress myostatin expression, and enhance skeletal muscle angiogenesis in
healthy people and some animal studies. The purpose of this study is mainly to investigate
the effects of exercise training on
1. circulating VEGF-A
2. muscle growth and function
3. Myostatin
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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