Non Small Cell Lung Cancer Clinical Trial
Official title:
Epidemiologic Study of KRAS Mutation in Brazilian Patients With Advanced or Metastatic Non Small Cell Lung Cancer
The purpose of this study is to characterize the demographic and clinical aspects, and describe the frequency and type of KRAS mutation in a Brazilian population sample with advanced non-small cell lung cancer (NSCLC).
Status | Completed |
Enrollment | 100 |
Est. completion date | April 2010 |
Est. primary completion date | April 2010 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Histological or cytological confirmation of locally advanced or metastatic Non Small Cell Lung Cancer (IIIB-IV) - Tumour sample (block of slides) available for KRAS analysis Exclusion Criteria: - Confirmation of locally advanced or metastatic NSCLC (IIIB-IV) exclusively by cytology, with no tumour sample access. - Previous treatment using a MEK inhibitor or any other regimen containing docetaxel (previous treatment with paclitaxel is accepted) |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Brazil | Research Site | Belo Horizonte | |
Brazil | Research Site | Porto Alegre | |
Brazil | Research Site | Rio de Janeiro | |
Brazil | Research Site | Santo André | |
Brazil | Research Site | São Paulo |
Lead Sponsor | Collaborator |
---|---|
AstraZeneca | Laboratorio Progenetica |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To analyze the frequency and type of KRAS mutation in a sample of the Brazilian population with advanced NSCLC. | March 31, 2010 | No |
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