Non-Small Cell Lung Cancer Clinical Trial
Official title:
Tumour Volume as an Independent Prognostic Factor in Patients With Non-Small Cell Lung Cancer - A Protocol for a Prospective Database.
The main aim is to determine, in patients with locoregional, non-small cell lung cancer (NSCLC) treated by definitive radiotherapy, the influence on survival of the volume of primary tumour, as measured from CT imaging, after adjusting for the effect of the current TNM staging system and other known prognostic factors (especially ECOG performance and weight loss).
Patients with locoregional non small cell lung cancer are registered on study after tumour
volumes are outlined by a radiologist and prior to the commencement of any treatment.
All patients must have recorded the volume of disease in the primary tumour (and of involved
nodes > 1 cm diameter) as measured from a CT scan performed according to a standard set of
conditions.
Following registration patients are treated with Definitive radiotherapy with or without
chemotherapy. Follow-up will occur with the collection of a minimum amount of data every 12
months from the date of registration on study.
Quality Assurance procedures will be implemented with each site that participates in the
study.
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Observational Model: Cohort, Time Perspective: Prospective
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