Non-small Cell Lung Cancer Clinical Trial
Official title:
Dynamic CT Perfusion for Assessment of Lung Cancer Before and After Neoadjuvant Chemo-/ Radiotherapy
Verified date | May 2017 |
Source | University Health Network, Toronto |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Cancer of the lung is treated with surgery, radiation or chemotherapy, depending on the
stage or extent of the disease. Some patients are treated with chemotherapy and/or radiation
therapy before surgery to improve the results of surgery. After these treatments, we do not
know whether the residual tumour tissue is still alive or dead, which is why some physicians
feel that surgery is required to remove it.
This study is designed to assess if computed tomography (CT, CAT-scan) enhanced with
intravenous contrast agent (dye) can characterize a lung cancer, and say whether it is alive
or dead. The researchers hope that in the future such a contrast-enhanced CAT-scan will make
surgery less often necessary or improve the results of chemotherapy and/or radiation given
before surgery.
Status | Completed |
Enrollment | 38 |
Est. completion date | October 2009 |
Est. primary completion date | October 2009 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - diagnosis of non-small cell lung cancer - Patients who are scheduled for any neo-adjuvant treatment Exclusion Criteria: - Females who are known to be pregnant or nursing - Patients with a history of adverse reaction to previous contrast agent administration - Patients with known renal disease |
Country | Name | City | State |
---|---|---|---|
Canada | University Health Network | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
University Health Network, Toronto |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | -Analysis will be performed to yield quantitative, absolute estimates of blood volume, blood flow, and microvascular permeability. | 2 months |
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