Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis — BATTLE  

Non-CF Bronchiectasis Clinical Trial

Official title: Long-term Inhaled Nebulized Tobramycin in Patients With Non-cystic Fibrosis Bronchiectasis. A Randomized Placebo Controlled Trial. The BATTLE Study Bronchiectasis And Tobramycin SoluTion InhaLation ThErapy.

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate the effect of tobramycin inhalation solution (TIS) once daily compared tot placebo in patients with non-CF bronchiectasis. The primary endpoint is a reduction of exacerbations of the disease during the treatment period. Next to this parameter the investigators expect to show a significant beneficial effect on lung function parameters, QoL, bacterial load of pathogens in sputum and tobramycin resistance.

Clinical Trial Description

See uploaded study protocol ;

Related Conditions & MeSH terms

• Bronchiectasis
• Non-CF Bronchiectasis

• NCT number: NCT02657473
• Study type: Interventional
• Source: Medical Center Alkmaar
• Status: Completed
• Phase: Phase 2/Phase 3
• Start date: August 13, 2016
• Completion date: December 13, 2019