Non Alcoholic Steatohepatitis Clinical Trial
Official title:
Clinical Study Evaluating the Efficacy and Safety of Montelukast in the Treatment of Non-Alcoholic Steatohepatitis (NASH)
the current study is to evaluate the efficacy and safety of Montelukast in the treatment of patients with non-alcoholic steatohepatitis (NASH).
This is a randomized, prospective placebo-controlled study that will be conducted on 44
patients who fulfill the selection criteria and will be classified randomly into two groups.
Group 1 (Control group n= 22): Patients will receive Placebo once daily at bedtime.
Group 2 (Treatment group n= 22): Patients will receive Montelukast 10 mg daily at bedtime.
The treatment duration will be 12 weeks. Patients will be recruited from National Liver
Institute and Fever, Liver and GIT disease Shebin El-Kom hospital, Egypt. All participants
will be informed about the nature of the study. The patients will give their informed
consent.The study will be approved by Research Ethics Committee of faculty of pharmacy -Tanta
University. Data of all patients will be private and confidential. Any unexpected risk will
be reported to patients and ethical committee on time
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