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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01240148
Other study ID # D3780C00005
Secondary ID
Status Completed
Phase Phase 1
First received November 10, 2010
Last updated April 11, 2011
Start date December 2010
Est. completion date March 2011

Study information

Verified date April 2011
Source AstraZeneca
Contact n/a
Is FDA regulated No
Health authority United Kingdom: Medicines and Healthcare Products Regulatory Agency
Study type Interventional

Clinical Trial Summary

The purpose of this study is to investigate the effect of AZD3161 on mechanical pain sensitivity and axon reflex flare in normal and ultraviolet C irradiated skin.


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Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science


Related Conditions & MeSH terms


Intervention

Drug:
AZD3161
Single dose, intradermal injection
Lidocaine
Single dose, intradermal injection
AZD3161 Placebo


Locations

Country Name City State
United Kingdom Research Site London

Sponsors (1)

Lead Sponsor Collaborator
AstraZeneca

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type Measure Description Time frame Safety issue
Primary Results of mechanical pain testing using Quantitative Sensory Testing Day 1 No
Secondary Number of participants with Adverse Events Range of 14 days Yes
Secondary Vital signs (blood pressure, heart rate, pulse) Day 1 Yes
Secondary Clinical chemistry (urinalysis, hematology) At follow up (a range of 8-15 days after Day 1) Yes
Secondary The effect of AZD3161 on axon reflex flare in normal and UVC irradiated skin using a Laser doppler scan Day 1 No
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