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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05882942
Other study ID # 22231905455
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date March 3, 2023
Est. completion date August 15, 2023

Study information

Verified date May 2024
Source University of Chichester
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.


Description:

Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.


Recruitment information / eligibility

Status Completed
Enrollment 8
Est. completion date August 15, 2023
Est. primary completion date July 26, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 30 Years
Eligibility Inclusion Criteria: - healthy - non-smokers - not taking any supplements - no known allergy to green tea Exclusion Criteria: - smokers - known high blood pressure - on medication

Study Design


Related Conditions & MeSH terms


Intervention

Dietary Supplement:
Matcha green tea
This is the condition with the Matcha green tea
Placebo
This is the condition with the placebo

Locations

Country Name City State
United Kingdom Mark Willems Chichester West Sussex
United Kingdom University of Chichester Chichester

Sponsors (1)

Lead Sponsor Collaborator
University of Chichester

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type Measure Description Time frame Safety issue
Primary Heart rate variability Measurement of root mean square of standard deviation of RR intervals Three weeks
Primary Carbohydrate oxidation Measurement of carbohydrate oxidation in grams/minute Three weeks
Primary Fat oxidation Measurement of fat oxidation in grams/minute Three weeks
Primary Cardiac output Measurement of cardiac output in liters per minute Three weeks
Primary Stroke volume Measurement of stroke volume in milliliters Three weeks
Primary Total peripheral resistance Measurement of total peripheral resistance in (mmHg x min) / mL Three weeks
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