Newborn Clinical Trial
Official title:
Study of Psychoactive Substances in Newborns' Hair Whose Mothers Were Treated and Followed at the Nice University Hospital - New Born Hair Study
Hair toxicological analysis is nowadays a complementary technique to blood and urinary
analyses because it allows a better detection of xenobiotics in time.
The detection of xenobiotics is expressed in hours in blood and in days in urines; it is
several months in the hair. So, hair makes it possible to establish a retrospective timetable
of consumption and exposure to xenobiotics.
In newborns, hair has different morphological characteristics than adults' hair. It is
thinner, more porous and the development phases are not the same.
Nevertheless, it is recognized that the absorption mechanisms of xenobiotics in newborns'
hair are similar to those of adults. On the other hand, some difficulties of interpretation
and discernment are observed between in utero exposure and environmental exposure after
birth.
It is interesting to have data to estimate the absorption of psychoactive substances in
newborns' hair following an utero exposure.
The main objective of this project is to study the mechanisms of incorporation of
psychoactive substances administered to the mothers during pregnancy in newborns' hair.
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