Fish Oil and Folate Supplementation During Pregnancy — NUHEAL  

Neurological Development Clinical Trial

Official title: Dietary Supply of Docosahexaenoic Acid (DHA) and 5-methyl-tetrahydro-folate (MTHF) During the Second Half of Pregnancy and Early Infancy

Status Completed

Clinical Trial Summary

Pregnant women are randomised to supplementation with fish oil, methyl tetrahydro folic acid, both or a placebo during the second half of pregnancy. Biochemical measures are determined in maternal blood during pregnancy and in cord blood.

Non invasive follow up examinations of infants at ages 4, 5.5, 6.5, 7.5, 8, 9 and 9.5 years focus on long term effects of supplementation anthropometric development, neurological development and allergy risk.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Neurological Development
• Perinatal DHA and Folate Status

• NCT number: NCT01180933
• Study type: Interventional
• Source: Ludwig-Maximilians - University of Munich
• Status: Completed
• Phase: N/A
• Start date: November 2001
• Completion date: March 2013