Neurocysticercosis Clinical Trial
Official title:
A Pilot Study of Neurocysticercosis Treatment
The purpose of this study is to determine if treatment with albendazole improves the clinical outcome of neurocysticercosis infection and/or leads to the disappearance of cysts sooner when compared with symptomatic treatment.
Status | Completed |
Enrollment | 178 |
Est. completion date | February 2005 |
Est. primary completion date | February 2005 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Patients presenting with new onset of symptoms associated with neurocysticercosis within two months of identification and have active and/or transitional neurocysticercosis cysts on computed tomography (CT) or magnetic resonance imaging (MRI) Exclusion Criteria: - Patients with only calcifications - Patients who are pregnant - Patients with one of the following conditions: papilledema, active tuberculosis, syphilis, ocular cysticercosis, active gastric ulcers, or a progressive and life-threatening disorder - Patients who received anthelmintic drugs (AHD) during the year preceding presentation or who received steroids within 30 days of presentation |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Ecuador | Vicente Corral Moscoso Hospital of Cuenca, Centro de Epilepsia, Facultad de Ciencias Médicinas de la Universidad de Cuenca IDIUC (Área 5), Av. 12 de Abril. Cdla. | Cuenca | |
Ecuador | Teodoro Maldonado Carbo Hospital, Av. 25 de Julio Vía Puerto Marítimo | Guayaquil | |
Ecuador | Baca Ortiz Children's Hospital, Av. Colon s/n y 6 de Diciembre | Quito | |
Ecuador | Hospital Carlos Andrade Marin, Av. 10 de agosto y Bogotá | Quito | |
Ecuador | Hospital Eugenio Espejo, Servicio de Neurología, Av. Colombia s/n | Quito |
Lead Sponsor | Collaborator |
---|---|
Columbia University | National Institute of Neurological Disorders and Stroke (NINDS) |
Ecuador,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cyst freedom | 1 month, 6 months, 1 year | No | |
Secondary | cyst reduction | 1 month, 6 months, 1 year | No | |
Secondary | seizure freedom | actuarial at 1 year | No |
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