Study of Cerebral Glucose Metabolism in Healthy Volunteers Using 18 F-FDG PET: Evaluation of the Effects of Aging, Comparative Evaluation of Neurodegenerative and Psychiatric Pathologies.

Neuro-Degenerative Disease Clinical Trial

Official title:

Study of Cerebral Glucose Metabolism in Healthy Volunteers Using 18 F-FDG PET: Evaluation of the Effects of Aging, Comparative Evaluation of Neurodegenerative and Psychiatric Pathologies.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06164938
• Other study ID #: FDG-NORM
• Status: Completed
• Start date: April 14, 2010
• Est. completion date: January 12, 2011

Study information

• Verified date: December 2023
• Source: IRCCS San Raffaele
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the study is to obtain information on cerebral glucose metabolism measured with the 18F-FDG PET technique in normal subjects without current or previous neurological or psychiatric pathologies in order to use the data obtained for voxel-based statistical analyzes for comparison with individual subjects ( patients with disease neurological or psychiatric) which will be evaluated with the same method to improve the specificity and diagnostic sensitivity of the FDG PET exam.

The objective is to obtain a functional measure of brain glucose metabolism in every normal subject because this is a functional measure of brain activity. The subjects will represent different decades of age to have a wider range of comparison with patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 23
• Est. completion date: January 12, 2011
• Est. primary completion date: January 12, 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

• absence of neurological and psychiatric pathologies, negative pregnancy test.

Related Conditions & MeSH terms

• Neuro-Degenerative Disease
• Neurodegenerative Diseases

Intervention

Diagnostic Test:
• Diagnostic accuracy
The aim is to obtain a regional measure of brain glucose metabolism in each normal subject because this is a functional measure of brain activity.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
IRCCS San Raffaele

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Study of glucose metabolism with 18 F FDG PET	Study of glucose metabolism with 18 F FDG PET in normal subjects without current or previous neurological or psychiatric pathologies in order to use the data obtained for statistical analyzes for comparison with individual subjects (patients with neurological or psychiatric) which will be evaluated with the same method to improve the diagnostic sensitivity of the FDG PET exam.	1 year