Pulsed Electromagnetic Field Therapy Versus Transcutaneous Electrical Nerve Stimulation in on Post-herpetic Neuralgia of the Sciatic Nerve

Neuralgia,Postherpetic Clinical Trial

Official title:

A Comparative Study Between Pulsed Electromagnetic Field Therapy and Transcutaneous Electrical Nerve Stimulation in Management of Post-herpetic Neuralgia of the Sciatic Nerve

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04488835
• Other study ID #: 68mm
• Status: Completed
• Phase: N/A
• Start date: March 10, 2018
• Est. completion date: October 15, 2019

Study information

• Verified date: August 2020
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Background and purpose: Post-herpetic neuralgia (PHN) is the most frequent chronic complication of herpes zoster, resulting in post- infectious severe neuropathic pain. Due to drug resistance severe pain; patients with PHN suffer from reduced physical activities, social and psychological manifestations as well as decrease in the quality of life. The purpose of this research was to evaluate the efficacy of pulsed electromagnetic field therapy (PEMFT) versus transcutaneous electrical nerve stimulation (TENS) in the treatment of post-herpetic neuralgia of the sciatic nerve.

Methods: In an eight weeks period of treatemnt, 52 patients were randomly and equally assigned into two groups. Both groups received conventional physical therapy treatment protocol. Moreover, group (A) has an additional TENS application and group (B) had PEMFS application. TENS and the PEMFT were applied once daily, three times per week for 20 minutes for each session. Assessment performed pre and post intervention using visual analogue scale (VAS) and estimation of the carbamazepine intake (CMI).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: October 15, 2019
• Est. primary completion date: March 20, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 30 Years to 40 Years

Eligibility

Inclusion Criteria:

• Age from 30-40 years

• History of herpes zoster more than 90 days

• Visual analogue scale is greater than or equal 5 out on a scale from 0 to 10

• All patients were on pain medication "Carbamazepine"

Exclusion Criteria:

• uncooperative behavior

• Intellectual disability to complete the self-evaluation questionnaires

Related Conditions & MeSH terms

• Neuralgia
• Neuralgia, Postherpetic
• Neuralgia,Postherpetic

Intervention

Other:
• Electromagnetic field therapy and transcutaneous electrical nerve stimulation
Both groups received conventional physical therapy treatment protocol. Moreover, group (A) has an additional TENS application and group (B) had PEMFS application. TENS and the PEMFT were applied once daily, three times per week for 20 minutes for each session. Assessment performed pre and post intervention using visual analogue scale (VAS) and estimation of the carbamazepine intake (CMI).

Locations

Country	Name	City	State
Egypt	Marwa Eid	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	neuralgia	Visual analogue scale for pain ,zero indicates no pain ten indicates maximum pain	8 weeks