Determination Of Dispersion In Ultrasound Guided Quadratus Lumborum Block

Status Not yet recruiting

Clinical Trial Summary

Lumbar Quadrant Blockade is a recent analgesic technique consisting of the injection of local anesthetic around the lumbar square muscle. It was initially described as a technique for abdominal wall analgesia, but later studies have increased the range of indications for laparoscopic and lower limb surgeries. There are several techniques described but with differences in the literature at the point of injection and volume of anesthetic. The exact mechanism of visceral analgesia has not yet been determined. The objective of this study is to determine the dispersion of local anesthetic as a variable dependent on the volume of local anesthetic and injection site and elucidate the mechanisms of analgesia.

Clinical Trial Description

After the free and informed consent signed by the family authorizing the procedure, demographic and clinical data will be collected from the medical records of the deceased. The corpse will be weighed, measured and placed on the autopsy table. Blockade randomization (QLB 2 or QLB 3) and volume of local anesthetic (10ml, 20ml, 30ml) will be performed for each side. Injection in the anterior or posterior plane to the Lumbar Quadrant muscle will be performed by anesthesiologists experienced in the technique with ultrasound aid. A colouring solution will be used. After confirming the correct needle position, the previously randomized volumes will be injected. After the blockage, the corpse will be placed in the supine position and will be submitted to autopsy by standard procedure. After removal of the thoracic and abdominal viscera, the investigators will verify the dispersion of the local anesthetic. Photographic records will be made and the number of levels by which the solution dispersed will be annotated, calculating the number of cranial and caudal levels. The corpse will then have its autopsy procedure completed, with the placement of the viscera and incision closure according to the service standard. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03545295
Study type	Interventional
Source	Federal University of São Paulo
Contact	Marcelo V Perez, PhD
Phone	+551121767000
Email	marcelovazperez@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	August 1, 2018
Completion date	May 31, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04633850` - Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
Completed	`NCT03652103` - Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy	Phase 4
Completed	`NCT03631914` - Intelligent Needle Tip Tracking Using Ultrasound Imaging for Infraclavicular Brachial Plexus Blocks	N/A
Completed	`NCT03244631` - Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection	N/A
Completed	`NCT05034601` - ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure	N/A
Completed	`NCT03740815` - Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection	N/A
Not yet recruiting	`NCT03978780` - Erector Spinae Block vs. Placebo Block Study	N/A
Not yet recruiting	`NCT04101019` - Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery	N/A
Recruiting	`NCT02903719` - The Effect of Phrenic Nerve Block on Postoperative Shoulder Pain in Patients for Liver Resection.	Phase 4
Completed	`NCT03211949` - Ultrasound Guided Topographic Mapping of Medial Antebrachial Cutaneous Nerve	N/A
Completed	`NCT05549011` - PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
Suspended	`NCT03291691` - Protective Nerve Stimulation in Regional Anesthesia
Completed	`NCT03771742` - Modified Paramedic Sagittal vs. Transverse TMQLB	N/A
Recruiting	`NCT04480320` - Sonography-guided Pericapsular Never Group Block for Hip Arthroplasty	N/A
Active, not recruiting	`NCT05555147` - The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy	N/A
Not yet recruiting	`NCT04298580` - Timing Effect of Ultrasound-Guided PVB After Robotic Cardiac Surgery	N/A
Completed	`NCT03658421` - Dexmedetomidine as Adjuvant for FNB in TKA	N/A
Completed	`NCT03667898` - Intelligent Needle Tip Tracking Using Ultrasound Imaging for Lumbar Plexus Blocks	N/A
Terminated	`NCT03316118` - US Guided GNB vs Saline Injection for TKA	Phase 4
Completed	`NCT03317600` - Postamputation Pain: Peripheral Mechanisms	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Determination Of Dispersion In Ultrasound Guided Quadratus Lumborum Block In Cadavers

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms