Nephropathy Clinical Trial
Official title:
Amniotic Fluid Biomarker Research for Prediction of Postnatal Renal Function in Fetus With a Bilateral Abnormal Renal Development: National, Multicenter, Prospective and Non-interventional Study.
The discovery of antenatal bilateral renal anomaly poses an essential question: can we
predict postnatal renal function? Ultrasound is insufficiently precise to predict postnatal
renal function evolution.
The objective of this study is to estimate the specificity and sensitivity of amniotic fluid
biomarkers to predict postnatal renal function in fetuses with bilateral developmental
nephropathies.
Both fetuses with bilateral renal anomalies and control (healthy) fetuses will be included.
For this study amniotic fluid will only be collected according to routine clinical practice
and only excess amniotic fluid sample will be used for the study.
The potentially identified biomarkers will not change routine management of the pregnancies
in the study.
n/a
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