Clinical Trials Logo

Clinical Trial Summary

The objective is to explore the effects of adding AC-134 on renal function, proteinuria, uremic toxins, and metabolism-related markers in chronic kidney disease.


Clinical Trial Description

Chronic kidney disease (CKD) management primarily focuses on addressing associated complications such as hypertension, diabetes mellitus, cardiovascular disease, and proteinuria. In addition to standard therapies, reducing the accumulation of toxins, particularly gut-derived uremic toxins like indoxyl sulfate (IS) and p-cresol sulfate (PCS), may help alleviate uremia symptoms. This study assesses the impact of oral AC-134 capsules containing activated charcoal adsorbent on CKD patients. The assessment will include evaluating changes in renal function, proteinuria, uremic toxins, and metabolism-related markers. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06441435
Study type Interventional
Source Taichung Veterans General Hospital
Contact Wen-Ching Yang
Phone (04)23592525
Email nutri1234@vghtc.gov.tw
Status Not yet recruiting
Phase N/A
Start date May 24, 2024
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Completed NCT00379899 - ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis Phase 4
Completed NCT00146224 - Efficacy of Epoetin Alfa Deep Tank in Treatment of Anemia in Patients With Chronic Kidney Disease Receiving Hemodialysis Phase 3
Recruiting NCT05991245 - French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"
Completed NCT00189501 - A Multi-Center, Observational Registry of Subjects With Secondary Hyperparathyroidism (HPT) and Chronic Kidney Disease (CKD) N/A
Completed NCT04122222 - Immune Response to Influenza Vaccine in ESRD Patients N/A